The worldwide incidence of preterm birth: a systematic review of maternal mortality and morbidity
The worldwide incidence of preterm birth: a systematic review of maternal mortality and morbidity
复制标题
DOI：
10.2471/blt.08.062554
复制
发表时间：
2010-01-01
期刊：
影响因子：
--
通讯作者：
Look, Paul FA Van
中科院分区：
文献类型：
--
作者：
Beck, Stacy;Wojdyla, Daniel;Look, Paul FA Van
目的分析世界范围内的早产发生率，以评估这一公共卫生问题的发生率，绘制早产的区域分布图，并了解现有的评估策略。方法从之前对1997年至2002年报告的已发表和未发表的孕产妇死亡率和发病率数据的系统回顾中提取世界范围内的早产率数据。这些数据通过涵盖2003-2007年期间的补充搜索得到补充。使用特定区域的多元回归模型来估计没有数据的国家的早产率。我们估计2005年有1290万新生儿早产，占全世界新生儿总数的9.6%。大约1100万（85%）。这些早产集中在非洲和亚洲，而欧洲和北美（不包括墨西哥）各有50万例，拉丁美洲和加勒比有90万例。早产率最高的是非洲和北美（分别占所有新生儿的11.9%和10.6%），最低的是欧洲（6.2%）。结论早产是全球范围内重要的围产期健康问题。发展中国家，特别是非洲和南亚的发展中国家，就绝对数字而言负担最重，尽管北美的比率也很高。为了更好地获得有效的产科和新生儿护理，需要在国家一级更好地了解早产的原因并改进对早产发生率的估计。
Objective To analyse preterm birth rates worldwide to assess the incidence of this public health problem, map the regional distribution of preterm births and gain insight into existing assessment strategies.Methods Data on preterm birth rates worldwide were extracted during a previous systematic review of published and unpublished data on maternal mortality and morbidity reported between 1997 and 2002. Those data were supplemented through a complementary search covering the period 2003-2007. Region-specific multiple regression models were used to estimate the preterm birth rates for countries with no data.Findings We estimated that in 2005, 12.9 million births, or 9.6% of all births worldwide, were preterm. Approximately 11 million (85%). of these preterm births were concentrated in Africa and Asia, while about 0.5 million occurred in each of Europe and North America (excluding Mexico) and 0.9 million in Latin America and the Caribbean. The highest rates of preterm birth were in Africa and North America (11.9% and 10.6% of all births, respectively), and the lowest were in Europe (6.2%).Conclusion Preterm birth is an important perinatal health problem across the globe. Developing countries, especially those in Africa and southern Asia, incur the highest burden in terms of absolute numbers, although a high rate is also observed in North America. A better understanding of the causes of preterm birth and improved estimates of the incidence of preterm birth at the country level are needed to improve access to effective obstetric and neonatal care.