Estrogenic modulation of auditory processing: a vertebrate comparison.
Estrogenic modulation of auditory processing: a vertebrate comparison.
复制标题
DOI：
10.1016/j.yfrne.2013.07.006
复制
发表时间：
2013-10
影响因子：
7.4
通讯作者：
Caras ML
中科院分区：
文献类型：
--
作者：
Caras ML
Sex-steroid hormones are well-known regulators of vocal motor behavior in several organisms. A large body of evidence now indicates that these same hormones modulate processing at multiple levels of the ascending auditory pathway. The goal of this review is to provide a comparative analysis of the role of estrogens in vertebrate auditory function. Four major conclusions can be drawn from the literature: First, estrogens may influence the development of the mammalian auditory system. Second, estrogenic signaling protects the mammalian auditory system from noise- and age-related damage. Third, estrogens optimize auditory processing during periods of reproductive readiness in multiple vertebrate lineages. Finally, brain-derived estrogens can act locally to enhance auditory response properties in at least one avian species. This comparative examination may lead to a better appreciation of the role of estrogens in the processing of natural vocalizations and may provide useful insights toward alleviating auditory dysfunctions emanating from hormonal imbalances.
