Aberrant Vascular Anatomy Associated With Artifactual Focal Avidity in the Liver on PSMA PET.
Aberrant Vascular Anatomy Associated With Artifactual Focal Avidity in the Liver on PSMA PET.
复制标题
PSMA PET 上与肝脏中人工局灶性亲和力相关的异常血管解剖结构。
DOI：
10.1097/rlu.0000000000004765
复制
发表时间：
2023
影响因子：
10.6
通讯作者：
Schuster,DavidM
中科院分区：
文献类型：
--
作者：
Lawal,IsmaheelO;Pectasides,Melina;Parihar,AshwinSingh;Shah,HardikU;Halkar,RaghuveerK;Jani,AsheshB;Schuster,DavidM
68 Ga–前列腺特异性膜抗原 (PSMA) PET/CT 是前列腺癌分期和再分期的重要工具。前列腺特异性膜抗原表达并非前列腺癌所特有的，因为它在正常组织以及肿瘤和非肿瘤过程中表达。认识到 PSMA 亲和力病变的广泛可能性对于识别正常变异并避免图像解读中的潜在陷阱是必要的。我们提出了一系列病例，显示肝段 IVb 中的生理局灶性 PSMA 亲和力。我们将这种摄取与异常的肝血管系统联系起来。认识到这种变异对于准确的图像解释非常重要，以防止额外的侵入性手术、不当的治疗升级以及拒绝对患者进行治疗。
68 Ga–prostate-specific membrane antigen (PSMA) PET/CT is a valuable tool for staging and restaging of prostate cancer. Prostate-specific membrane antigen expression is not specific to prostate cancer, as it is expressed in normal tissues as well as in neoplastic and nonneoplastic processes. Awareness of the broad possibility of lesions with PSMA avidity is necessary to recognize normal variants and avoid potential pitfalls in image interpretation. We present a series of cases showing physiologic focal PSMA avidity in hepatic segment IVb. We correlate this uptake with aberrant hepatic vasculature. The awareness of this variant is important for accurate image interpretation to prevent additional invasive procedures, undue treatment escalation, and denial of curative treatment to patients.