link-ancestors: fast simulation of local ancestry with tree sequence software.
link-ancestors: fast simulation of local ancestry with tree sequence software.
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DOI:
10.1093/bioadv/vbad163
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发表时间:
2023
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It is challenging to simulate realistic tracts of genetic ancestry on a scale suitable for simulation-based inference. We present an algorithm that enables this information to be extracted efficiently from tree sequences produced by simulations run with msprime and SLiM. A C-based implementation of the link-ancestors algorithm is in tskit (https://tskit.dev/tskit/docs/stable/). We also provide a user-friendly wrapper for link-ancestors in tspop, a Python-based utility package.
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影响因子:
4.3
作者:
Kelleher J;Etheridge AM;McVean G
通讯作者:
McVean G
影响因子:
3.3
作者:
Ralph,Peter;Thornton,Kevin;Kelleher,Jerome
通讯作者:
Kelleher,Jerome
影响因子:
3.3
作者:
Baumdicker, Franz;Bisschop, Gertjan;Goldstein, Daniel;Gower, Graham;Ragsdale, Aaron P.;Tsambos, Georgia;Zhu, Sha;Eldon, Bjarki;Ellerman, E. Castedo;Galloway, Jared G.;Gladstein, Ariella L.;Gorjanc, Gregor;Guo, Bing;Jeffery, Ben;Kretzschumar, Warren W.;Lohse, Konrad;Matschiner, Michael;Nelson, Dominic;Pope, Nathaniel S.;Quinto-Cortes, Consuelo D.;Rodrigues, Murillo F.;Saunack, Kumar;Sellinger, Thibaut;Thornton, Kevin;van Kemenade, Hugo;Wohns, Anthony W.;Wong, Yan;Gravel, Simon;Kern, Andrew D.;Koskela, Jere;Ralph, Peter L.;Kelleher, Jerome
通讯作者:
Kelleher, Jerome
影响因子:
10.7
作者:
Haller, Benjamin C.;Messer, Philipp W.
通讯作者:
Messer, Philipp W.
影响因子:
7.7
作者:
Schumer, Molly;Powell, Daniel L.;Corbett-Detig, Russ
通讯作者:
Corbett-Detig, Russ