Cystoid puncture for chronic cystoid macular oedema

Cystoid puncture for chronic cystoid macular oedema
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囊样穿刺治疗慢性黄斑囊样水肿

DOI:
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发表时间:
2007
影响因子:
4.1
通讯作者:
P. Kaiser
P. Kaiser
中科院分区:
医学2区
文献类型:
--
作者:
Rishi P. Singh;R. Margolis;P. Kaiser

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目的:探讨膀胱样黄斑水肿穿刺治疗标准治疗难治性慢性黄斑水肿的新技术。方法:回顾性分析血管性视网膜病变引起的慢性囊样黄斑水肿患者,其最大的药物或手术治疗失败,并接受了玻璃体切割和CMOP。观察治疗前后的临床表现、最佳矫正Snellen视力、立体彩色眼底摄影、静脉荧光素血管造影、光学相干断层扫描,以评价治疗的有效性和安全性。结果:7例患者纳入研究。膀胱样斑水肿5例为糖尿病视网膜病变,1例为视网膜中央静脉阻塞,1例为视网膜分支静脉阻塞。所有患者术前玻璃体内类固醇治疗均失败,其中3例患者也行焦点网格光凝治疗。先前的玻璃体平面肌切除术,后玻璃体抬高,内部限制膜剥离和玻璃体内类固醇注射,在3例患者中失败。到CMOP的中位时间为488天。所有患者均通过荧光素血管造影或光学相干断层扫描(或两者兼而有之)确定囊样水肿的消退或改善。然而,5例患者的视力没有变化,1例患者视力下降,1例患者视力稳定。结论:虽然CMOP后囊样黄斑水肿确实得到了定量改善,但该技术未能改善患者的视力。
Objective: To evaluate the new surgical technique of cystoid macular oedema puncture (CMOP) in patients with longstanding cystoid macular oedema refractory to standard treatments. Design: Interventional, retrospective case series Methods: Retrospective review of patients with chronic cystoid macular oedema from vascular retinopathy for whom maximal medical or surgical treatment failed and who underwent pars plana vitrectomy and CMOP. Clinical findings, best-corrected Snellen visual acuity, stereo colour fundus photography, intravenous fluorescein angiograms, and optical coherence tomography were obtained before and after treatment to evaluate the efficacy and safety of the treatment. Results: Seven patients were included in the study. Cystoid macular oedema was due to diabetic retinopathy in five patients, central retinal vein occlusion in one patient and branch retinal vein occlusion in one patient. Preoperative intravitreal steroids failed for all patients, and three patients also had focal grid photocoagulation. Previous pars plana vitrectomy, with elevation of the posterior hyaloid, internal limiting membrane peeling, and intravitreal steroid injection, had failed in three patients. The median time to CMOP was 488 days. Resolution or improvement of cystoid oedema occurred in all patients as determined by fluorescein angiography or optical coherence tomography, or both. However, visual acuity was unchanged in five patients, declined in one patient and stable in one patient. Conclusions: Although cystoid macular oedema does improve quantitatively after CMOP, the technique fails to improve visual acuity in patients.
DOI: 10.1016/j.fbio.2022.102294
发表时间: 2022-12-13
期刊: FOOD BIOSCIENCE
影响因子: 5.2
作者:
Liu,Songqi;Chen,Zaihan;Deng,Lingli
通讯作者: Deng,Lingli