Putting Evidence Into Practice: An Update of Evidence-Based Interventions for Cancer-Related Fatigue During and Following Treatment
Putting Evidence Into Practice: An Update of Evidence-Based Interventions for Cancer-Related Fatigue During and Following Treatment
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DOI：
10.1188/14.cjon.s3.38-58
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发表时间：
2014-12-01
影响因子：
1.1
通讯作者：
Weisbrod, Breanna L.
中科院分区：
文献类型：
--
作者：
Mitchell, Sandra A.;Hoffman, Amy J.;Weisbrod, Breanna L.
癌症相关性疲劳（CRF）对身体，社会，认知和职业功能产生有害影响，并导致患者及其家人的情绪和精神痛苦;然而，它仍然没有得到充分的认识和治疗。本文批判性地回顾并整合了支持CRF药物和非药物治疗方法疗效的现有经验证据，强调了自2007年和2009年将证据付诸实践出版物以来的新证据。建议练习或可能有效改善疲劳结果的干预措施包括运动;筛查可治疗的风险因素;并发症状的管理;瑜伽;结构化康复;威斯康星州人参;失眠，疼痛和抑郁的认知行为疗法;基于正念的减压;以及心理教育干预措施，如预期指导、心理社会支持、节能和活动管理。这些信息可用于改善CRF的管理，为卫生政策和项目开发提供信息，塑造CRF新疗法的临床试验设计，并推动基础和转化研究。
Cancer-related fatigue (CRF) has deleterious effects on physical, social, cognitive, and vocational functioning, and causes emotional and spiritual distress for patients and their families; however, it remains under-recognized and undertreated. This article critically reviews and integrates the available empirical evidence supporting the efficacy of pharmacologic and nonpharmacologic treatment approaches to CRF, highlighting new evidence since 2007 and 2009 Putting Evidence Into Practice publications. Interventions that are recommended for practice or likely to be effective in improving fatigue outcomes include exercise; screening for treatable risk factors; management of concurrent symptoms; yoga; structured rehabilitation; Wisconsin ginseng; cognitive-behavioral therapies for insomnia, pain, and depression; mindfulness-based stress reduction; and psychoeducational interventions such as anticipatory guidance, psychosocial support, and energy conservation and activity management. This information can be applied to improve the management of CRF, inform health policy and program development, shape the design of clinical trials of new therapies for CRF, and drive basic and translational research.