Activity energy expenditure and change in body composition in late life
Activity energy expenditure and change in body composition in late life
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DOI：
10.3945/ajcn.2009.27659
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发表时间：
2009-11-01
影响因子：
7.1
通讯作者：
Harris, Tamara B.
中科院分区：
文献类型：
--
作者：
Manini, Todd M.;Everhart, James E.;Harris, Tamara B.
背景：老年人身体成分的改变，特别是脱脂质量的减少和脂肪质量的增加，是导致功能衰退和身体残疾的主要途径。目的：目的：确定与运动相关的能量消耗与老年男性和女性身体质量和组成变化的关系。设计：采用双标记水法对302名70-82岁的社区老年人进行2wk的总能量消耗(TEE)评估。用间接量热法测量静息代谢率(RMR)，估计饮食的热效应为TEE的10%。活动能量消耗(AEE)计算为[TEE(0.9)-RMR]。每年用双能X线骨密度仪测量总体质量、脱脂质量(FFM)和脂肪质量(FM)，平均(+/-SD)为4.9+/-1.3。结果：在调整了基线年龄、吸烟状况和种族的多因素模型中，男性和女性的体质量(kg/y)均有下降(男性：-0.34，95%CI：-0.71，0.02；女性：-0.45，95%可信区间：-0.71，-0.19；女性男性：-0.48，95%可信区间：-0.67，-0.29；女性：-0.14，95%可信区间：-0.026，-0.03。男性：0.14，95%可信区间：-0.10，0.38；女性：-0.28，95%可信区间：-0.49，-0.07。在男性和女性中，基线时较高的AEE与较大的FFM相关。然而，这些结果(即斜率)的平均变化在不同年龄的AEE中是相似的。结论：这些数据表明，所有体力活动的累积能量消耗与更大的FFM有关，但这种影响不会改变FFM在晚年的变化轨迹。AM J Clin Nutr 2009；90：1336-42。
Background: Change in body composition, specifically loss of fat-free mass and gain in fat mass, in older adults is a major pathway leading to the onset of functional decline and physical disability.Objective: The objective was to determine the association of activity-related energy expenditure with change in body mass and composition among older men and women.Design: Total energy expenditure ( TEE) was assessed over 2 wk by using the doubly labeled water method in 302 community-dwelling older adults aged 70-82 y. Resting metabolic rate (RMR) was measured by using indirect calorimetry, and the thermic effect of meals was estimated at 10% of TEE. Activity energy expenditure (AEE) was calculated as [TEE(0.9) - RMR]. Total body mass, fat-free mass (FFM), and fat mass ( FM) were assessed by dual-energy X-ray absorptiometry annually over a mean (+/- SD) of 4.9 +/- 1.3 y.Results: In multivariate models adjusted for baseline age, smoking status, and race, men and women had a decline ( in kg/y) in body mass ( men: -0.34, 95% CI: -0.71, 0.02; women: -0.45, 95% CI: -0.71, -0.19) and FFM ( men: -0.48, 95% CI: -0.67, -0.29; women: -0.14, 95% CI: -0.026, -0.03). No changes (in kg/y) were observed in FM ( men: 0.14, 95% CI: -0.10, 0.38; women: -0.28, 95% CI: -0.49, -0.07). In men and women, higher AEE at baseline was associated with greater FFM. The average change in these outcomes (ie, slope), however, was similar across tertiles of AEE.Conclusions: These data suggest that accumulated energy expenditure from all physical activities is associated with greater FFM, but the effect does not alter the trajectory of FFM change in late life. Am J Clin Nutr 2009; 90: 1336-42.