Vitamin D deficiency in pregnant women from a non-European ethnic minority population - an interventional study
Vitamin D deficiency in pregnant women from a non-European ethnic minority population - an interventional study
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DOI：
10.1111/j.1471-0528.2002.01171.x
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发表时间：
2002-08-01
影响因子：
5.8
通讯作者：
Richards, B
中科院分区：
文献类型：
--
作者：
Datt, S;Alfaham, M;Richards, B
目的了解南威尔士州非欧洲少数民族孕妇的维生素D状况。设计前瞻性研究。地点：Llandough医院，卡迪夫。南威尔士。样本160名孕妇从非欧洲少数民族人口在南Wales.Methods进行了第一次产前检查的维生素D状况的生化筛查。发现缺乏维生素D的妇女随后补充和维生素D的状态进行复查，在delivery.Main outcome measure维生素D status at delivery.Results八十160名妇女有一个维生素D水平低于8 ng/mL，在他们的第一次产前检查和口服维生素D治疗。可能影响维生素D状况的因素，如宗教、英语流利程度和着装习惯，似乎没有任何影响。尽管在英国生活超过三年的女性中，维生素D水平低于正常水平的比例较高。在58检查在分娩时，平均血浆维生素D水平从6增加到11 ng/mL，虽然平均甲状旁腺激素水平是不变的。结论鉴于低正常维生素D水平的妇女从少数民族的高发病率，我们建议这些妇女在怀孕早期的生化筛查，随后补充的指示。
Objective To determine the vitamin D status of pregnant women from non-European ethnic minorities in South Wales.Design Prospective study.Setting Llandough Hospital, Cardiff. South Wales.Sample One hundred and sixty pregnant women from a non-European ethnic minority population in South Wales.Methods Biochemical screening of vitamin D status was carried out at the first antenatal visit. Women found to be deficient in vitamin D were subsequently supplemented and vitamin D status was rechecked at delivery.Main outcome measure Vitamin D status at delivery.Results Eighty of 160 women had a vitamin D level below 8 ng/mL at their first antenatal visit and were treated with oral vitamin D. Factors that could influence vitamin D status such as religion, fluency in English and dressing habits did not appear to have any effect. although a higher proportion of women who had lived in Britain for longer than three years had subnormal vitamin D levels. In 58 of those checked at delivery, the mean plasma vitamin D level increased from 6 to 11 ng/mL although the mean parathyroid hormone level was unchanged.Conclusion In view of the high incidence of subnormal vitamin D levels in women from ethnic minorities, we recommend biochemical screening of these women in early pregnancy, with subsequent supplementation where indicated.