Dark-field signal extraction in propagation-based phase-contrast imaging
Dark-field signal extraction in propagation-based phase-contrast imaging
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DOI：
10.1088/1361-6560/abac9d
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发表时间：
2020-11-07
影响因子：
3.5
通讯作者：
Quiney, H. M.
中科院分区：
文献类型：
--
作者：
Gureyev, T. E.;Paganin, D. M.;Quiney, H. M.
提出了一种基于传播型相衬成像的暗场信号提取方法。在物体主要由单一材料或几种不同材料组成的情况下，该方法需要一幅图像来提取二维投影成像中的暗场信号，这些材料的实部减量与复折射率虚部的比率相似。在三维层析成像的情况下，该方法只需要在每个投影角度采集一幅图像。使用模拟和实验数据的初步例子表明，该方法可以改善对较大对象内部微小尖锐特征的可视化，例如基于传播的X射线乳腺癌成像中的微钙化的可视化。研究表明，该方法可用于其他形式的生物医学成像，在不增加样品辐射剂量的情况下，可以帮助人们获得额外的小角散射信息。
A method for extracting the dark-field signal in propagation-based phase-contrast imaging is proposed. In the case of objects consisting predominantly of a single material, or several different materials with similar ratios of the real decrement to the imaginary part of the complex refractive index, the proposed method requires a single image for extraction of the dark-field signal in two-dimensional projection imaging. In the case of three-dimensional tomographic imaging, the method needs only one image to be collected at each projection angle. Initial examples using simulated and experimental data indicate that this method can improve visualization of small sharp features inside a larger object, e.g. the visualization of microcalcifications in propagation-based x-ray breast cancer imaging. It is suggested that the proposed approach may be useful in other forms of biomedical imaging, where it can help one to obtain additional small-angle scattering information without increasing the radiation dose to the sample.