Effects of treadmill exercise on transcranial magnetic stimulation-induced excitability to quadriceps after stroke
Effects of treadmill exercise on transcranial magnetic stimulation-induced excitability to quadriceps after stroke
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DOI：
10.1016/j.apmr.2005.10.016
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发表时间：
2006-02-01
影响因子：
4.3
通讯作者：
Macko, RF
中科院分区：
文献类型：
--
作者：
Forrester, LW;Hanley, DF;Macko, RF
Objective: To determine characteristics of transcranial magnetic stimulation (TMS)-induced measures of central motor excitability to the paretic and nonparetic quadriceps muscles of chronic hemiparetic stroke patients in the context of a short-term, submaximal bout treadmill exercise.Design: Cross-sectional.Setting: Motor control and gait biomechanics laboratory.Participants: Convenience sample of 11 patients including cohorts of treadmill untrained (n=8) and trained (n=3) stroke patients with chronic hemiparetic gait.Intervention: Short-term submaximal treadmill exercise.Main Outcome Measures: Thresholds, amplitudes and latencies of TMS-induced motor evoked potentials at vastus medialis in paretic and nonparetic lower extremities.Results: Baseline characteristics of the motor evoked potentials (MEPs) show significantly higher motor thresholds, longer latencies, and reduced amplitudes on the paretic side. In cross-sectional comparisons a group of treadmill-trained patients had greater paretic MEP amplitude changes after treadmill exercise versus paretic MEP responses from a group of untrained patients.Conclusions: These results indicate that treadmill training for 3 months or more may alter responsiveness of the lower-extremity central motor pathways to a short-term treadmill stimulus.
