The frequency and the role of Chlamydia trachomatis infection in premature labor
The frequency and the role of Chlamydia trachomatis infection in premature labor
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DOI：
10.1016/s0020-7292(98)00075-7
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发表时间：
1998-07-01
影响因子：
3.8
通讯作者：
Nyári, T
中科院分区：
文献类型：
--
作者：
Kovács, L;Nagy, E;Nyári, T
目的：探讨沙眼衣原体（C。（见上文第10段）在一项前瞻性、代表性、多中心研究中，对感染在早产病因中的作用进行了研究。方法：采用Gen-Probe法对7个中心的6161例受试者进行检测。结果：感染率为5.74%。低出生体重、胎膜早破、发育不良与C。tr.感染在威胁早产的情况下，C的感染率显着更高。文-阳性患者在低出生体重和围产儿死亡的情况下，母亲C。tr.感染率明显高于正常妊娠。C. h.-用罗红霉素治疗的阳性患者有足月分娩。贫穷的社会环境和高C之间的相关性。tr，感染率可证实。结论：对有不良孕产史和/或社会高危人群应进行C. tr.感染，并在积极的情况下，建议治疗。(C)1998年国际妇产科联合会。
Objective: The importance of Chlamydia trachomatis (C. tr.) infection in the etiology of premature labor was examined in a prospective, representative, multicenter study. Method: Specimens were collected from 6161 subjects in seven centers and examined by the Gen-Probe method. Results: The infection rate was 5.74%. There were no significant correlations between low birth weight, premature rupture of the membranes, dysmaturity and C. tr. infection. In cases of threatening premature labor, the infection rate was significantly higher in C. tr.-positive patients. In the event of combined low birth weight and perinatal death, the maternal C. tr. infection rate was significantly higher than in normal pregnancies. C. h.-positive patients treated with roxithromycin had term deliveries. A correlation between poor social circumstances and a high C. tr, infection rate could be proved. Conclusion: Cases with a poor obstetric history and/or socially high-risk patients should be screened for C. tr. infection, and in positive cases treatment is recommended. (C) 1998 International Federation of Gynecology and Obstetrics.