Pulmonary arterial pruning is associated with CT-derived bronchiectasis progression in smokers.
Pulmonary arterial pruning is associated with CT-derived bronchiectasis progression in smokers.
复制标题
肺动脉修剪与吸烟者 CT 衍生的支气管扩张进展相关。
DOI：
10.1016/j.rmed.2022.106971
复制
发表时间：
2022
影响因子：
4.3
通讯作者：
Diaz,AlejandroA
中科院分区：
文献类型：
--
作者：
Dolliver,WojciechR;Wang,Wei;Nardelli,Pietro;Rahaghi,FarbodN;Orejas,JoseL;Maselli,DiegoJ;Yen,Andrew;Young,Kendra;Kinney,Gregory;Estépar,RaulSanJosé;Diaz,AlejandroA
以<5 mm2横截面动脉血管体积与总动脉血管体积（BV5a/TBVa）之比来衡量的肺动脉小动脉的损失，越低表明切除越多，与吸烟者的5年进展性ct衍生支气管扩张相关（优势比（OR）[95%置信区间]，每降低5%的BV5a/TBVa为1.28 [1.07-1.53],P = 0.007）。COPD吸烟者的相应结果为：每降低5% BV5a/TBVa， OR为1.45 [1.11-1.89],P = 0.007。结果支持血管因素对支气管扩张的结构性进展。
Loss of small pulmonary arteries measured as the ratio of blood vessel volume in arteries <5 mm2in cross-section to total arterial blood vessel volume (BV5a/TBVa), with lower values indicating more pruning, was associated with 5-yr progressing CT-derived bronchiectasis in smokers (Odds Ratio (OR) [95% Confidence interval], 1.28 [1.07–1.53] per 5% lower BV5a/TBVa, P = 0.007). Corresponding results in smokers with COPD were: OR 1.45 [1.11–1.89] per 5% lower BV5a/TBVa, P = 0.007. The results support a vascular factor for structural progression of bronchiectasis.