Formation of SERS active nanoparticle assemblies via specific carbohydrate-protein interactions

Formation of SERS active nanoparticle assemblies via specific carbohydrate-protein interactions
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DOI:
10.1039/c2cc36949d
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发表时间:
2013-01-01
影响因子:
4.9
通讯作者:
Graham, Duncan
Graham, Duncan
中科院分区:
化学2区
文献类型:
--
作者:
Craig, Derek;Simpson, Jonathan;Graham, Duncan

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设计了一个开/关Sers聚集系统,用于研究碳水化合物-凝集素相互作用。凝集素ConA的检测在皮科水平实现。还证明了两种不同碳水化合物部分之间的区别,证明了碳水化合物和存在的特定蛋白质之间的特异性相互作用。
An on/off SERS aggregation system has been designed to investigate carbohydrate-lectin interactions. Detection of the lectin ConA was achieved at pico molar levels. Discrimination was also demonstrated between two different carbohydrate moieties demonstrating the specific interaction between the carbohydrate and specific protein present.