Aerobic and anaerobic exercise capacity in adolescents with juvenile idiopathic arthritis
Aerobic and anaerobic exercise capacity in adolescents with juvenile idiopathic arthritis
复制标题
DOI：
10.1002/art.22897
复制
发表时间：
2007-08-15
期刊：
影响因子：
--
通讯作者：
Armbrust, Wineke
中科院分区：
文献类型：
--
作者：
Lelieveld, Otto T. H. M.;van Brussel, Marco;Armbrust, Wineke
目标。检测青少年特发性关节炎(JIA)患者的有氧和无氧运动能力，并与年龄和性别匹配的健康人进行比较，评估疾病相关变量与有氧和无氧运动能力之间的关系。在JIA过渡门诊登记的25名患者中，22名JIA患者纳入本研究(平均+/-SD年龄17.1+/-0.7岁，范围16-18岁)。有氧能力的测定采用症状受限自行车测功法。无氧能力用Wingate厌氧试验进行评估。采用儿童健康评定量表进行功能能力评定。疼痛和总体幸福感是使用视觉模拟标尺测量的。并对患者的病程和疾病活动性进行评估。与健康对照组相比，JIA组的绝对和相对最大耗氧量明显受损(男生分别为85%和83%；女生分别为81%和78%)。平均功率也显著受损(男孩为88%，女孩为74%)，而女孩的峰值功率显著受损，男孩则没有显著意义(女孩为67%，男孩为92%)。对体重不足和超重进行校正后的分析表明，身体成分对结果没有实质性影响。这项研究表明，与年龄和性别匹配的健康同龄人相比，患有JIA的青少年有氧和无氧运动能力受损。这种显着损害的可能原因是多因素的，需要揭示以改进治疗策略。
Objective. To examine the aerobic and anaerobic exercise capacity in adolescents with juvenile idiopathic arthritis (JIA) compared with age- and sex-matched healthy individuals, and to assess associations between disease-related variables and aerobic and anaerobic exercise capacity.Methods. Of 25 patients enrolled in a JIA transition outpatient clinic, 22 patients with JIA were included in this study (mean +/- SD age 17.1 +/- 0.7 years, range 16-18 years). Aerobic capacity was examined using a Symptom Limited Bicycle Ergometry test. Anaerobic capacity was assessed with the Wingate Anaerobic Test. Functional ability was assessed with the Childhood Health Assessment Questionnaire. Pain and overall well-being were measured using a visual analog scale. Disease duration and disease activity were also assessed.Results. Absolute and relative maximal oxygen consumption in the JIA group were significantly impaired (85% and 83% for boys, respectively; 81% and 78% for girls, respectively) compared with healthy controls. Mean power was also significantly impaired (88% for boys and 74% for girls), whereas peak power was significantly impaired for girls and just failed significance for boys (67% for girls and 92% for boys). A post hoc analysis correcting for underweight and overweight demonstrated that body composition did not influence the results substantially.Conclusion. This study demonstrated that adolescents with JIA have an impaired aerobic and anaerobic exercise capacity compared with healthy age- and sex-matched peers. The likely cause for this significant impairment is multifactorial and needs to be revealed to improve treatment strategies.