Similarities and differences in memory deficits in patients with primary dementia and depression-related cognitive dysfunction.
Similarities and differences in memory deficits in patients with primary dementia and depression-related cognitive dysfunction.
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原发性痴呆和抑郁相关认知功能障碍患者记忆缺陷的异同。
DOI：
10.1176/jnp.5.3.277
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发表时间：
1993
期刊：
影响因子：
--
通讯作者：
Markwalter,HR
中科院分区：
文献类型：
--
作者：
Hill,CD;Stoudemire,A;Morris,R;Martino-Saltzman,D;Markwalter,HR
作者研究了单独患有重性抑郁症（MD）的老年患者的言语记忆表现之间的差异;伴有可逆性抑郁相关认知功能障碍（MD/DRCD）的重性抑郁症;以及原发性痴呆和重性抑郁症（DEM/MD）。在抗抑郁治疗前和治疗后6个月和15个月对患者进行评估。在这三组中，单独患有MD的患者在加州言语学习测试中获得了更多的信息，并表现出更明显的首因效应。DEM/MD患者更容易犯入侵错误。虽然老年抑郁症患者与MD/DRCD可能类似于患者与DEM/MD的言语记忆性能的某些方面，差异可能会被观察到的学习错误的类型。诊断的影响进行了讨论。
The authors examined differences between the verbal memory performance of older patients with major depression (MD) alone; major depression with reversible depression-related cognitive dysfunction (MD/DRCD); and primary dementia and major depression (DEM/MD). Patients were evaluated before antidepressant treatment and 6 and 15 months after treatment. Of the three groups, patients with MD alone acquired significantly more information on the California Verbal Learning Test and showed a more pronounced primacy effect. Patients with DEM/MD were more likely to commit errors of intrusion. Although older depressed patients with MD/DRCD may resemble patients with DEM/MD on some aspects of verbal memory performance, differences may be observed in the types of learning errors they commit. Diagnostic implications are discussed.