Randomised controlled trial of compliance therapy - 18-month follow-up

Randomised controlled trial of compliance therapy - 18-month follow-up
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DOI:
10.1192/bjp.172.5.413
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发表时间:
1998-05-01
影响因子:
10.5
通讯作者:
David, A
David, A
中科院分区:
医学1区
文献类型:
--
作者:
Kemp, R;Kirov, G;David, A

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背景:一项随机对照试验在急性治疗环境中进行,以检查依从性治疗的有效性,这是一种基于动机访谈和最近精神病认知方法的针对精神障碍治疗依从性的简短实用干预。方法选取74例符合DSM-III-R标准的急性住院患者,接受4-6次依从性治疗或非特异性咨询,随访18个月以上。主要结果测量是观察者评价的依从性、对治疗的态度、洞察力和社会功能。结果依从性治疗组在治疗后的洞察力、对治疗的态度和观察者评价依从性方面具有显著优势,这些指标在随访期间保持不变。随着时间的推移,与对照组相比,依从性治疗组的整体社会功能改善相对更多。依从性治疗组再入院前在社区的生存时间明显更长。结论依从性治疗对改善急性精神病发作后患者的功能和社区生活的有效性。
Background A randomised controlled trial was conducted in an acute treatment setting to examine the effectiveness of compliance therapy, a brief pragmatic intervention targeting treatment adherence in psychotic disorders, based on motivational interviewing and recent cognitive approaches to psychosis.Method Seventy-four patients with psychotic disorders according to DSM-III-R criteria recruited from consecutive admissions to an acute in-patient unit, received 4-6 sessions of either compliance therapy or non-specific counselling, and were followed-up over 18 months. The principal outcome measures were observer-rated compliance, attitudes to treatment, insight and social functioning.Results Significant advantages were found for the compliance therapy group post-treatment on measures of insight, attitudes to treatment and observer-rated compliance which were retained over the follow-up period. Global social functioning improved relatively more over time in the compliance therapy group compared with the control group. Survival in the community prior to readmission was significantly longer in the compliance therapy group.Conclusions The results support the effectiveness of compliance therapy in improving functioning and community tenure after an acute psychotic episode.