THE GAMMA-GLOBULINS AND THEIR CLINICAL SIGNIFICANCE .4. THERAPEUTIC USES OF GAMMA-GLOBULINS
THE GAMMA-GLOBULINS AND THEIR CLINICAL SIGNIFICANCE .4. THERAPEUTIC USES OF GAMMA-GLOBULINS
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DOI：
10.1056/nejm195901222600406
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发表时间：
1959-01-01
影响因子：
158.5
通讯作者：
JANEWAY, CA
中科院分区：
文献类型：
--
作者：
GROSS, PAM;GITLIN, D;JANEWAY, CA
（结论）* γ球蛋白的临床应用在第二次世界大战期间，由于美国红十字会采购了大量的血浆库，以及人类血浆分离技术的成功发展，从人类血浆中分离γ球蛋白用于预防和治疗传染病成为可能。尽管丙种球蛋白组分（Cohn的组分II）几乎含有所有抗许多细菌和病毒的血浆抗体，但任何给定批次丙种球蛋白的特异性抗体含量完全取决于供体血浆中存在的特定免疫抗体。浓度和品种.
(Concluded)*Clinical Uses of Gamma GlobulinThe separation of gamma globulins from human plasma for use in the prevention and treatment of infectious diseases was made possible during World War II by the procurement of large plasma pools by the American Red Cross and by the successful development of human plasma-fractionation technics. Although the gamma-globulin fraction (fraction II of Cohn) contains almost all the plasma antibodies against many bacteria and viruses, the specific antibody content of any given lot of gamma globulin depends entirely upon the particular immune antibodies present in the plasma of the donors. The concentration and variety . . .