Rural residence and adoption of a novel HIV therapy in a national, equal-access healthcare system.
Rural residence and adoption of a novel HIV therapy in a national, equal-access healthcare system.
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DOI:
10.1007/s10461-011-0107-8
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发表时间:
2013-01
影响因子:
4.4
通讯作者:
Vaughan-Sarrazin, Mary
中科院分区:
文献类型:
--
作者:
Ohl, Michael;Lund, Brian;Belperio, Pamela S.;Goetz, Matthew Bidwell;Rimland, David;Richardson, Kelly;Justice, Amy;Perencevich, Eli;Vaughan-Sarrazin, Mary
Rural persons with HIV face barriers to care that may influence adoption of advances in therapy. We performed a retrospective cohort study to determine rural–urban variation in adoption of raltegravir—the first HIV integrase inhibitor—in national Veterans Afffairs (VA) healthcare. There were 1,222 veterans with clinical indication for raltegravir therapy at time of its FDA approval in October 2007, of whom 223 (19.1%) resided in rural areas. Urban persons were more likely than rural to initiate raltegravir within 180 days (17.3% vs. 11.2%, P = 0.02) and 360 days (27.5% vs. 19.7%, P = 0.02), but this gap narrowed slightly at 720 days (36.3% vs. 31.8%, P = 0.19). In multivariable analysis adjusting for patient characteristics, urban residence predicted raltegravir adoption within 180 days (odds ratio 1.72, 95% CI 1.09–2.70) and 360 days (OR 1.63, 95% CI 1.13–2.34), but not 720 days (OR 1.26, 95% CI 0.84–1.87). Efforts are needed to reduce geographic variation in adoption of advances in HIV therapy.
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影响因子:
--
作者:
Ding, L;Landon, BE;Cleary, PD
通讯作者:
Cleary, PD
DOI:
10.1097/00126334-200010010-00005
发表时间:
2000-10-01
期刊:
JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
影响因子:
--
作者:
Cunningham, WE;Markson, LE;Wenger, NS
通讯作者:
Wenger, NS
DOI:
10.1016/s0140-6736(08)61113-7
发表时间:
2008-07-26
期刊:
Lancet (London, England)
影响因子:
--
作者:
Antiretroviral Therapy Cohort Collaboration
通讯作者:
Antiretroviral Therapy Cohort Collaboration
影响因子:
3
作者:
STEINER, JF;KOEPSELL, TD;INUI, TS
通讯作者:
INUI, TS
DOI:
10.1080/713612410
发表时间:
1998-06-01
影响因子:
1.7
作者:
Heckman, TG;Somlai, AM;Kelly, JA
通讯作者:
Kelly, JA