Development and testing of a five-item version of the Geriatric Depression Scale

Development and testing of a five-item version of the Geriatric Depression Scale
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DOI:
10.1111/j.1532-5415.1999.tb03848.x
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发表时间:
1999-07-01
影响因子:
6.3
通讯作者:
Rubenstein, LZ
Rubenstein, LZ
中科院分区:
医学1区
文献类型:
--
作者:
Hoyl, MT;Alessi, CA;Rubenstein, LZ

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目的:开发和测试五项版本的老年抑郁量表(GDS)在筛查虚弱的社区居住老年人抑郁方面的有效性。设计:横断面研究。地点:加州塞普尔韦达退伍军人医疗中心(Sepulveda VA Medical Center)的老年门诊。参与者:共有74名虚弱的门诊患者(98.6%为男性,平均年龄74.6岁)参加了一项正在进行的试验。测量:受试者有一个全面的老年评估,包括有老年精神病学咨询的抑郁症的结构化临床评估。从15个条目的GDS中选择Pearson chi(2)与抑郁症临床诊断相关性最高的条目,创建了一个s条目版本的GDS。计算15项GDS量表和新的5项GDS量表的敏感性、特异性、诊断准确性、阳性预测值和阴性预测值。结果:受试者的平均GDS评分为6.2(范围0-15)。临床评估发现46%的受试者患有抑郁症。抑郁组和非抑郁组在人口统计学、精神状态、教育水平和慢性疾病数量方面相似。以临床评价作为抑郁症的金标准,5项GDS(与括号中15项GDS结果相比)的敏感性为。97(。94),特异性。85(。83),阳性预测值。85(。82),负预测值。97(。94),准确性。90(0.88)。抑郁诊断与5项GDS有显著的一致性(kappa = 0.81)。还测试了其他多种简短形式,并对其进行了讨论。5项和15项GDS的平均给药时间为。分别为9分钟和2.7分钟。结论:在该人群中,s项GDS与15项GDS在抑郁症筛查方面同样有效,且给药时间显著缩短。如果在其他地方得到验证,它可能被证明是抑郁症的首选筛查试验。
OBJECTIVE: To develop and test the effectiveness of a 5-item version of the Geriatric Depression Scale (GDS) in screening for depression in a frail community-dwelling older population.DESIGN: A cross-sectional study.SETTING: A geriatric outpatient clinic at the Sepulveda VA Medical Center, Sepulveda, California.PARTICIPANTS: A total of 74 frail outpatients (98.6% male, mean age 74.6) enrolled in an ongoing trial.MEASUREMENTS: Subjects had a comprehensive geriatric assessment that included a structured clinical evaluation for depression with geropsychiatric consultation. A S-item version of the GDS was created from the 15-item GDS by selecting the items with the highest Pearson chi(2) correlation with clinical diagnosis of depression. Sensitivity, specificity, diagnostic accuracy, and positive and negative predictive values were calculated for the 15-item GDS and the new 5-item scale.RESULTS: Subjects had a mean GDS score of 6.2 (range 0-15). Clinical evaluation found that 46% of subjects were depressed. The depressed and not depressed groups were similar with regard to demographics, mental status, educational level, and number of chronic medical conditions. Using clinical evaluation as the gold standard for depression, the 5-item GDS (compared with the 15-item GDS results shown in parentheses) had a sensitivity of .97 (.94), specificity of .85 (.83), positive predictive value of .85 (.82), negative predictive value of .97 (.94), and accuracy of .90 (.88) for predicting depression. Significant agreement was found between depression diagnosis and the 5-item GDS (kappa = 0.81). Multiple other short forms were tested, and are discussed. The mean administration times for the 5- and 15-item GDS were .9 and 2.7 minutes, respectively.CONCLUSIONS: The S-item GDS was as effective as the 15-item GDS for depression screening in this population, with a marked reduction in administration time. If validated elsewhere, it may prove to be a preferred screening test for depression.