Evaluation of Quality of Life and Severity of Depression, Anxiety, and Stress in Patients After Kidney Transplantation
Evaluation of Quality of Life and Severity of Depression, Anxiety, and Stress in Patients After Kidney Transplantation
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DOI：
10.1016/j.transproceed.2018.04.026
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发表时间：
2018-07-01
影响因子：
0.9
通讯作者：
Szarpak, L.
中科院分区：
文献类型：
--
作者：
Czyzewski, L.;Frelik, P.;Szarpak, L.
导论.终末期肾病（ESRD）对患者的生活质量（QoL）有显著影响。终末期肾病的最佳治疗方法是肾移植（KTx），其目的是延长和改善生活质量。本研究的目的是评估KTx患者的生活质量。我们的研究包括118名KTx后患者。用于评估的研究工具是由标准化工具组成的问卷：36项简表（SF-36）;肾脏疾病生活质量（KDQOL）量表;以及抑郁、焦虑和压力（DASS）量表。此外，还向患者提供了自己的体重和身高信息，然后计算体重指数。相关性分析显示，年龄对一般健康（R=0.191，P= 0.039）、身体功能（R=-0.295，P= 0.001）和一般身体健康（R=-0.275，P= 0.003）评估的影响具有统计学意义。自KTx以来，受试者的抑郁、焦虑和压力的平均严重程度随着时间的推移而变化。对于研究的KTx后时期（即10年），观察到以下变化：抑郁，分别为14.0 vs 11.2 vs 13.1;焦虑，分别为15.6 vs 9.8 vs 14.0;压力，分别为22.0 vs 13.5 vs 16.8。在本研究中，我们发现：1。KTx治疗后患者的生活质量显示出良好的日常生活功能水平，2。一般健康评估、身体功能、疼痛、睡眠质量、职业状况、活力、社会活动、工作人员支持和护理质量是KTx后与QoL相关的主要因素。
Introduction. End-stage renal disease (ESRD) has a significant impact on a patient's quality of life (QoL). The optimal treatment for ESRD is kidney transplantation (KTx), which aims to extend and improve QoL. The aim of the study was to assess a QoL in KTx recipients.Methods. Our study included 118 post-KTx patients. The research tool employed for assessment was a questionnaire consisting of standardized instruments: the 36-item Short Form (SF-36); the Kidney Disease Quality of Life (KDQOL) instrument; and the Depression, Anxiety, and Stress (DASS) scale. In addition, patients were provided with information on their own weight and height, followed by calculation of body mass index.Results. Correlation analysis showed a statistically significant influence of age on general health (R=0.191, P=.039), physical functioning (R= -0.295, P=.001), and general physical health (R= -0.275, P=.003) assessment. The mean severity of depression, anxiety, and stress among subjects changed over time since KTx. For the post-KTx periods studied (ie, 10 years), the following changes were observed: for depression, 14.0 vs 11.2 vs 13.1, respectively; for anxiety, 15.6 vs 9.8 vs 14.0, respectively; and for stress, 22.0 vs 13.5 vs 16.8, respectively.Conclusion. In this study we found that: 1. QoL in patients after KTx showed a good level for everyday life functioning, and 2. general health assessment, physical functioning, pain, sleep quality, occupational status, vitality, social activity, staff support, and quality of care were major factors associated with QoL after KTx.