Roles of the extracellular matrix in retinal development and maintenance.
Roles of the extracellular matrix in retinal development and maintenance.
复制标题
细胞外基质在视网膜发育和维护中的作用。
DOI:
10.1007/978-3-540-46826-4_7
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发表时间:
2000
影响因子:
--
通讯作者:
D. D. Hunter
中科院分区:
文献类型:
--
作者:
R. Libby;W. Brunken;D. D. Hunter
The extracellular matrix (ECM) is a highly organized meshwork of secreted macromolecules that consists of proteins, proteoglycans, and polysaccharides. Components of the ECM provide cells with different signals that are involved in many aspects of the development of multicellular organisms, such as: (1) when to start, continue, or stop dividing; (2) when to differentiate; (3) where to migrate; (4) how to polarize; (5) where to form a synapse; and (6) whether to die or survive. Thus, ECM molecules may be playing many different roles in the development of a complex tissue such as the retina.
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