Endovascular Aneurysm Sealing (EVAS) and Chimney EVAS in the Treatment of Failed Endovascular Aneurysm Repairs

Endovascular Aneurysm Sealing (EVAS) and Chimney EVAS in the Treatment of Failed Endovascular Aneurysm Repairs
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DOI:
10.1177/1526602816675622
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发表时间:
2017-02-01
影响因子:
2.6
通讯作者:
Dorweiler, Bernhard
Dorweiler, Bernhard
中科院分区:
医学2区
文献类型:
--
作者:
Youssef, Marwan;Zerwes, Sebastian;Dorweiler, Bernhard

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目的:评价Nellix血管内动脉瘤密封(EVAS)系统治疗血管内动脉瘤修复(EVAR)术后并发症的技术成功和临床效果。方法:于2014年3月至2015年12月在2家医院连续15例(平均年龄79岁,男性14例)既往有EVAR的患者接受EVAS治疗。先前失败的EVARs包括13例分岔内移植物,1例分岔内移植物加开窗袖带,1例管内移植物。Endoleaks是主要适应症:Ia型10例,III型5例(IIIa型3例,IIIb型2例)。所有患者均表现为进行性主动脉瘤(中位直径7.85 cm,范围6.5-11)。8例患者接受紧急治疗(6例有症状的动脉瘤,2例有破裂)。所有的患者都接受了Nellix修复失败的支架;由于近端着陆区不足,10例采用烟囱(Ch)程序结合EVAS (chEVAS)。结果:技术成功率100%。所有的裂缝都被成功密封,不需要额外的干预。EVAS或chEVAS后未见进一步渗漏。1例出现囊内突出,无后遗症。1例老年动脉瘤破裂患者术后2个月死于多器官功能衰竭。一例肾动脉导丝损伤因活动性出血而行肾切除术。在中位随访8个月(范围3-24个月)期间,未观察到再干预、动脉瘤相关死亡、移植物血栓形成、内漏或烟囱移植物闭塞。结论:目前的初步经验表明,EVAS/chEVAS治疗EVAR失败是可行的。当其他既定方法不可行或不可用时,该技术可作为救助或替代治疗。
Purpose: To assess the technical success and clinical outcome of reinterventions using the Nellix Endovascular Aneurysm Sealing (EVAS) System to treat complications after endovascular aneurysm repair (EVAR). Methods: Fifteen consecutive patients (mean age 79 years; 14 men) with prior EVAR were treated with EVAS between March 2014 and December 2015 at 2 institutions. The failed prior EVARs included 13 bifurcated endografts, 1 bifurcated graft plus fenestrated cuff, and 1 tube endograft. Endoleaks were the predominant indications: type Ia in 10 and type III in 5 (3 type IIIa and 2 type IIIb). All patients presented with progressive aortic aneurysms (median 7.85-cm diameter; range 6.5-11). Eight patients were treated on an urgent or emergency basis (6 symptomatic aneurysms and 2 contained ruptures). All patients underwent Nellix relining of the failed stent-graft; 10 had chimney (Ch) procedures in combination with EVAS (chEVAS) because the proximal landing zones were inadequate. Results: Technical success was 100%. All endoleaks were successfully sealed, and no additional intervention was required. No further endoleak after EVAS or chEVAS was recorded. Endobag protrusion occurred in 1 case without sequelae. One elderly patient with ruptured aneurysm died from multiple organ failure 2 months postoperatively. One renal artery guidewire injury led to nephrectomy because of active bleeding. No reinterventions, aneurysm-related mortalities, graft thrombosis, endoleaks, or chimney graft occlusions were observed during a median follow-up of 8 months (range 3-24). Conclusion: The present preliminary experience demonstrates that the use of EVAS/chEVAS is feasible for treatment of failed EVAR. This technique may be used as bailout or an alternative treatment when other established methods are infeasible or not available.