The adult with a Fontan operation.
The adult with a Fontan operation.
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DOI：
10.1007/bf02938382
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发表时间：
2007-07-01
影响因子：
3.7
通讯作者：
Child, John S
中科院分区：
文献类型：
--
作者：
Aboulhosn, Jamil;Child, John S
自1971年起，进行了Fontan手术以修复单心室生理。这项巧妙的手术将单心室纳入体循环，并利用心血管和呼吸生理学将脱氧血液推向肺部，从而最大限度地减少从右向左分流和紫绀。 Fontan 手术最初是作为右心房至肺动脉吻合术进行的，经历了不断演变的步骤，导致死亡率、发病率和结果逐渐改善。右心房纳入缓慢流动的 Fontan 回路会导致进行性扩张和持续性心律失常。这促使人们努力进行修改，将中庭部分或完全排除在 Fontan 回路之外。经导管完成的 Fontan 手术已在少数患者中进行，我们预计微创、经导管和混合干预措施将在这些患者的未来治疗中发挥重要作用。
Since 1971, the Fontan operation has been performed for the repair of single-ventricle physiology. This ingenious operation commits a single ventricle to the systemic circulation and takes advantage of cardiovascular and respiratory physiology to propel deoxygenated blood to the lungs, thus minimizing right-to-left shunting and cyanosis. Initially performed as a right atrial to pulmonary artery anastomosis, the Fontan operation has gone through evolutionary steps that have resulted in progressive improvements in mortality, morbidity, and outcomes. Inclusion of the right atrium in the slow-flowing Fontan circuit results in progressive dilation and incessant arrhythmias. This spurred forth efforts to create modifications that partially or completely exclude the atrium from the Fontan circuit. The transcatheter completion of the Fontan operation has been performed in a small number of patients and we expect minimally invasive, transcatheter, and hybrid interventions to play an important role in the future management of these patients.