Short‐Term Catecholamine Response to Psychological Stress1
Short‐Term Catecholamine Response to Psychological Stress1
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儿茶酚胺对心理压力的短期反应1
作者：
J. Dimsdale;J. Moss
患者;血浆儿茶酚胺放射酶测定法和高度便携式非突发性抽血泵的最新发展，使研究对实际应激的生理反应成为可能。然而，由于血浆儿茶酚胺的半衰期很短，因此必须小心翼翼地获得与压力浸泡体验一致的血液样本。这些观点在一项对10名面临公开演讲压力的年轻医生的研究中得到了证明。血浆肾上腺素水平在公开演讲的开始时刻和演讲的中间时刻之间有显著差异。这些差异大到足以影响在比较公共演讲值和基线值时得出的结论。
&NA; The recent development of radioenzymatic assays for plasma catecholamines and of highly portable nonobtrusive blood withdrawal pumps makes possible the investigation of the physiological response to actual stress. However because the half‐life of plasma catecholamines is so brief, meticulous care must be taken to obtain blood samples consistently vis‐a‐vis the stress immersion experience. These points are demonstrated in a study of ten young physicians under the stress of public speaking. Plasma epinephrine levels differ significantly between the initial moments of public speaking and the middle moments of speaking. These differences are large enough to affect the conclusions reached in comparing public speaking values with baseline values.