Cellular and molecular changes in mammary epithelial cells following irradiation.
Cellular and molecular changes in mammary epithelial cells following irradiation.
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辐射后乳腺上皮细胞的细胞和分子变化。
DOI：
10.2307/3578016
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发表时间：
1991
影响因子：
3.4
通讯作者：
R. Ullrich
中科院分区：
文献类型：
--
作者：
R. Ullrich
本文介绍了在过去几年中进行的实验，主要集中在乳腺肿瘤的发展，在BALB/c小鼠中子和γ射线照射后。本文描述了裂变能谱中子和137 Cs γ射线辐照后诱发乳腺和肺肿瘤的时间-剂量关系。随后的研究使用体内/体外方法来表征细胞和分子变化。这些研究表明，中子和伽马射线的影响在数量和质量上存在差异。
The present paper describes experiments conducted over the last several years which have focused primarily on the development of mammary tumors in BALB/c mice after neutron and gamma irradiation. Time-dose relationships for induction of mammary and lung tumors following irradiation with fission-spectrum neutrons and 137Cs gamma rays are described. Subsequent studies have used in vivo/in vitro approaches to characterize cellular and molecular changes. These studies suggest quantitative and qualitative differences in the effects of neutrons and gamma rays.
体内暴露于γ辐射和/或7,12-二甲基苯并[a]蒽的BALB/c小鼠乳腺上皮的体外增殖和体内致瘤潜力增强。
影响因子：
11.2
作者：
Adams,LM;Ethier,SP;Ullrich,RL
通讯作者：
Ullrich,RL