Conformational analysis of cycloalkanes
Conformational analysis of cycloalkanes
复制标题
DOI：
10.1007/s40828-015-0014-0
复制
发表时间：
2015-09-01
期刊：
影响因子：
2.4
通讯作者：
Dragojlovic, Veljko
中科院分区：
文献类型：
--
作者：
Dragojlovic, Veljko
构象分析是有机化学的一个相对较新的领域，它在有机反应、有机化合物中的键合和立体化学理论之后得到了很好的发展。直到二十世纪下半叶，它的重要性才得到充分认识，并认识到它在有机化合物的键合、反应性和稳定性方面的核心作用。构象分析的基本概念、小环和普通环构象分析的深入讨论以及中环和大环构象分析的介绍，以适合有机化学入门课程的水平进行介绍。本讨论旨在更好地理解不同类型应变之间的复杂关系，同时还讨论决定特定构象稳定性的因素。最后，探讨了每一类环烷烃的独特性质。
Conformational analysis is a comparatively new area of organic chemistry that has been developed well after the theories of organic reactions, bonding in organic compounds and stereochemistry. It was only in the second half of twentieth century that its importance was fully recognized and its central role with respect to bonding, reactivity and stability of organic compounds was appreciated. Fundamental concepts of conformational analysis, a deeper discussion of the conformational analysis of small and common rings and an introduction into the conformational analysis of medium and large rings are presented at a level suitable for an introductory organic chemistry course. This discussion aims to provide a better understanding of the complex relationship among different types of strain, while also discussing the factors that determine stability of a particular conformation. Finally, the unique nature of each class of cycloalkanes is explored.