MONONUCLEAR CELL SUBSETS AND CORONARY-ARTERY LESIONS IN KAWASAKI-DISEASE

MONONUCLEAR CELL SUBSETS AND CORONARY-ARTERY LESIONS IN KAWASAKI-DISEASE
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DOI:
10.1136/adc.67.6.706
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发表时间:
1992-06-01
影响因子:
5.2
通讯作者:
YABUTA, K
YABUTA, K
中科院分区:
医学2区
文献类型:
--
作者:
FURUKAWA, S;MATSUBARA, T;YABUTA, K

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本文对川崎和冠状动脉病变患者外周血单个核细胞亚群进行了研究。106例患者中有14例出现病变。与无冠状动脉病变的川崎病患者相比,有冠状动脉病变的川崎病患者的CD 14+巨噬细胞/单核细胞计数增加。CD 14+巨噬细胞/单核细胞的绝对计数是确定急性川崎期间血管损伤严重程度的重要参数。
The peripheral blood mononuclear cell subsets in patients with Kawasaki disease and coronary artery lesions were investigated. Of the 106 patients 14 had lesions. Patients with Kawasaki disease and coronary artery lesions were found to have increased counts of CD14+ macrophages/monocytes compared with those of patients with Kawasaki disease without lesions. The absolute counts of CD14+ macrophages/monocytes form an important parameter to determine the severity of vascular damage during acute Kawasaki disease.