How smoking affects sleep: A polysomnographical analysis
How smoking affects sleep: A polysomnographical analysis
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DOI：
10.1016/j.sleep.2012.06.026
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发表时间：
2012-12-01
期刊：
影响因子：
4.8
通讯作者：
Riemann, Dieter
中科院分区：
文献类型：
--
作者：
Jaehne, Andreas;Unbehaun, Thomas;Riemann, Dieter
目的：与不吸烟者相比，吸烟者的主观睡眠质量受到损害，但关于多导睡眠图 (PSG) 睡眠特征差异的方法学合理研究证据有限。因此，本研究使用 PSG 来评估吸烟者和非吸烟者的睡眠，同时控制影响睡眠的其他参数。方法：经过一个适应夜后，从 44 名吸烟者（29 名男性和 15 名女性，中位年龄 29.6 岁）获得 PSG 睡眠实验室数据，并与 44 名健康、性别和年龄匹配的从不吸烟者的 PSG 数据进行比较。排除标准是酒精或其他药物滥用、精神或内分泌疾病以及任何精神药物治疗。测量了（吸烟组）尼古丁和可替宁血浆水平，并评估了两组的主观睡眠质量。 结果：吸烟者的 Fagerstrom 耐受评分为 6.4，平均每天吸 21.2 支香烟，吸烟时间为 13.1 年（中位数）。与不吸烟者相比，吸烟者的睡眠周期时间较短、睡眠潜伏期较长、快速动眼睡眠密度较高、睡眠呼吸暂停和腿部运动较多。睡眠脑电图频谱分析参数以及 PSG 测量的睡眠效率没有差异。然而，与不吸烟者相比，吸烟者在匹兹堡睡眠质量指数上的睡眠效率较低，但在 SF-A 上没有发现差异。吸烟组的血浆可替宁水平与慢波睡眠呈负相关。结论：吸烟者表现出许多类似失眠的睡眠障碍。研究结果表明，睡眠研究人员在分析中控制吸烟状况非常重要。进一步的研究应集中于戒烟期间睡眠受损的原因和后果，因为睡眠障碍是初次戒烟后早期复发的已知危险因素。 (C) 2012 年由 Elsevier B.V. 出版
Objective: Subjective quality of sleep is impaired in smokers compared with non-smokers, but there is only limited evidence from methodologically sound studies about differences in polysomnography (PSG) sleep characteristics. Therefore, this study used PSG to evaluate sleep in smokers and non-smokers while controlling for other parameters that affect sleep.Methods: After an adaptation night, PSG sleep laboratory data were obtained from 44 smokers (29 men and 15 women, median age 29.6 years) and compared with PSG data from 44 healthy, sex- and age-matched never smokers. Exclusion criteria were alcohol or other substance abuse, psychiatric or endocrine diseases, and treatment with any kind of psychotropic medication. Nicotine and cotinine plasma levels were measured (in the smoking group) and subjective sleep quality assessed in both groups.Results: The smokers had a Fagerstrom tolerance score of 6.4, consumed an average of 21.2 cigarettes per day and had been smoking for 13.1 years (median). Smokers had a shorter sleep period time, longer sleep latency, higher rapid eye movement sleep density, more sleep apneas and leg movements in sleep than non-smokers. There were no differences regarding parameters of spectral analysis of the sleep electroencephalogram as well as in the sleep efficiency measured by PSG. Nevertheless smokers rated their sleep efficiency lower on the Pittsburgh Sleep Quality Index compared with non-smoking individuals, but no differences were detected on the SF-A. Plasma cotinine level correlated negatively with slow wave sleep in the smoking group.Conclusions: Smokers showed a number of insomnia-like sleep impairments. The findings suggest that it is important for sleep researchers to control smoking status in their analyses. Further research should focus on the causes and consequences of impaired sleep during tobacco cessation, as sleep disturbances are a known risk factor for early relapse after initial tobacco abstinence. (C) 2012 Published by Elsevier B.V.