Blood vessel deformations on microsecond time scales by ultrasonic cavitation.
Blood vessel deformations on microsecond time scales by ultrasonic cavitation.
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DOI：
10.1103/physrevlett.106.034301
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发表时间：
2011-01-21
影响因子：
8.6
通讯作者：
Matula TJ
中科院分区：
文献类型：
--
作者：
Chen H;Kreider W;Brayman AA;Bailey MR;Matula TJ
利用高速显微摄影研究了超声、微泡和微血管之间的瞬时相互作用。我们观察到液体射流、血管扩张（对周围组织的向外运动）和血管内陷（朝向管腔的向内运动）。与目前的范例相反，液体射流被引导远离最近的血管壁，并且内陷超过扩张。这些观察提供了深入了解气泡-血管相互作用的力学，这似乎定性地取决于生物组织的机械特性。
Transient interactions among ultrasound, microbubbles, and microvessels were studied using high-speed photomicrography. We observed liquid jets, vessel distention (motion outward against the surrounding tissue), and vessel invagination (motion inward toward the lumen). Contrary to current paradigms, liquid jets were directed away from the nearest vessel wall and invagination exceeded distention. These observations provide insight into the mechanics of bubble-vessel interactions, which appear to depend qualitatively upon the mechanical properties of biological tissues.