A universal menopausal syndrome?
A universal menopausal syndrome?
复制标题
DOI：
10.1016/j.amjmed.2005.09.057
复制
发表时间：
2005-12-19
期刊：
影响因子：
--
通讯作者：
Colvin, Alicia
中科院分区：
文献类型：
--
作者：
Avis, Nancy E;Brockwell, Sarah;Colvin, Alicia
各种症状经常被报告为更年期综合征的一部分。这些症状包括潮热、盗汗、月经不调、阴道干燥、抑郁、神经紧张、心悸、头痛、失眠、精力不足、难以集中注意力和头晕。对于那些想知道哪些症状可归因于更年期，哪些症状可归因于衰老或其他身体或心理因素的女性来说，症状是否以及如何一起发生的问题很重要。为了解决这个问题，本文探讨了以下研究途径：（1）症状的聚类或分组;（2）不同症状与绝经过渡阶段的时间关联;（3）不同文化，种族和民族之间症状报告的一致性;（4）症状风险因素的一致性。因素分析研究的结果不支持一个单一的综合征组成的更年期和心理或躯体症状。在整个过渡期的症状报告的患病率也反对更年期综合征，因为血管痉挛症状遵循不同于其他症状的独特模式。跨文化差异表明症状报告并不普遍。最后，虽然有一些重叠的危险因素的症状，绝经状态更一致地与血管紧张症状比心理或身体的。这些调查的结果都反对普遍的更年期综合征。未来的研究应该集中在症状是如何相互关联的，哪些因素与血管痉挛症状独特相关，并确定是否有一个亚组的妇女谁更有可能报告症状。
A variety of symptoms are reported frequently as being part of a menopausal syndrome. These include hot flashes, night sweats, menstrual irregularities, vaginal dryness, depression, nervous tension, palpitations, headaches, insomnia, lack of energy, difficulty concentrating, and dizzy spells. The question of whether and how symptoms occur together is important for women who want to know which symptoms can be attributed to menopause and which to aging generally or to other physical or psychosocial factors. To address this question, the present article examines the following avenues of research: (1) the clustering or grouping of symptoms; (2) the temporal association of different symptoms with stages of the menopausal transition; (3) the consistency of symptom reporting across cultures, race, and ethnicity; and (4) the consistency of risk factors for symptoms. Results of the factor analysis studies do not support a single syndrome consisting of menopausal and psychological or somatic symptoms. The prevalence of symptom reporting across the transition also argues against a menopausal syndrome because vasomotor symptoms follow a unique pattern that differs from that of other symptoms. Cross-cultural differences suggest that symptom reporting is not universal. Finally, although there is some overlap in risk factors for symptoms, menopausal status is more consistently related to vasomotor symptoms than to psychological or physical ones. Results of these investigations all argue against a universal menopausal syndrome. Future research should focus on how symptoms are interrelated, what factors are uniquely related to vasomotor symptoms, and identifying whether there is a subgroup of women who are more likely to report symptoms.