Effect of low perceived social support on health outcomes in young patients with acute myocardial infarction: results from the VIRGO (Variation in Recovery: Role of Gender on Outcomes of Young AMI Patients) study.
Effect of low perceived social support on health outcomes in young patients with acute myocardial infarction: results from the VIRGO (Variation in Recovery: Role of Gender on Outcomes of Young AMI Patients) study.
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DOI：
10.1161/jaha.114.001252
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发表时间：
2014-09-30
影响因子：
5.4
通讯作者：
Krumholz HM
中科院分区：
文献类型：
--
作者：
Bucholz EM;Strait KM;Dreyer RP;Geda M;Spatz ES;Bueno H;Lichtman JH;D'Onofrio G;Spertus JA;Krumholz HM
社会支持是急性心肌梗死（AMI）后健康结局的重要预测因素，但社会支持因性别和年龄而异。社会支持的差异可以解释年轻AMI患者预后的性别差异。本研究使用了来自恢复变化：性别对年轻AMI患者结局的作用（VIRGO）研究的数据，该研究是一项在美国和西班牙年龄≤55岁的AMI患者中进行的观察性研究。使用ENRICHD社会支持量表将患者分为低与中/高感知社会支持。结局包括基线和12个月时评估的健康状况（简表-12身体和精神分量评分）、抑郁症状（患者健康问卷）和心绞痛相关生活质量（西雅图心绞痛问卷）。在3432例患者中，21.2%被归类为低社会支持。男性和女性在基线时的社会支持水平相当。平均而言，社会支持低的患者在基线和AMI后12个月报告了较低的功能状态和生活质量以及更多的抑郁症状。经过多变量校正，包括基线健康状况，低社会支持与12个月时较低的心理功能，较低的生活质量和更多的抑郁症状相关（均P<0.001）。调整后，低社会支持与身体功能差之间的关系不显著（P=0.6）。社会支持，性别，或国家之间没有相互作用。在年轻男性和女性中，较低的社会支持与AMI后12个月更差的健康状况和更多的抑郁症状相关。性别并没有改变社会支持的效果。
Social support is an important predictor of health outcomes after acute myocardial infarction (AMI), but social support varies by sex and age. Differences in social support could account for sex differences in outcomes of young patients with AMI. Data from the Variation in Recovery: Role of Gender on Outcomes of Young AMI Patients (VIRGO) study, an observational study of AMI patients aged ≤55 years in the United States and Spain, were used for this study. Patients were categorized as having low versus moderate/high perceived social support using the ENRICHD Social Support Inventory. Outcomes included health status (Short Form‐12 physical and mental component scores), depressive symptoms (Patient Health Questionnaire), and angina‐related quality of life (Seattle Angina Questionnaire) evaluated at baseline and 12 months. Among 3432 patients, 21.2% were classified as having low social support. Men and women had comparable levels of social support at baseline. On average, patients with low social support reported lower functional status and quality of life and more depressive symptoms at baseline and 12 months post‐AMI. After multivariable adjustment, including baseline health status, low social support was associated with lower mental functioning, lower quality of life, and more depressive symptoms at 12 months (all P<0.001). The relationship between low social support and worse physical functioning was nonsignificant after adjustment (P=0.6). No interactions were observed between social support, sex, or country. Lower social support is associated with worse health status and more depressive symptoms 12 months after AMI in both young men and women. Sex did not modify the effect of social support.