Survey on chronic pancreatitis in the Asia-Pacific region
Survey on chronic pancreatitis in the Asia-Pacific region
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DOI：
10.1111/j.1440-1746.2004.03426.x
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发表时间：
2004-09-01
影响因子：
4.1
通讯作者：
Tandon, RK
中科院分区：
文献类型：
--
作者：
Garg, PK;Tandon, RK
背景和目的：对亚太地区不同国家的慢性胰腺炎（CP）进行了调查。调查的主要目的是产生一个数据库，包含有关的患病率，病因，临床表现，诊断工作，并在亚太地区CP的管理。方法：数据收集来自七个国家使用结构化问卷。专家参与者被要求回答的调查问卷的基础上的数据与CP患者在他们的centers.Results研究：CP的患病率被发现是非常高的，在印度南部（114-200/10万人口），在日本的低报告率为4.2/10万人口。酒精是澳大利亚（95%）和日本（54%）最常见的病因，而特发性胰腺炎是印度（热带胰腺炎）和中国最常见的类型，约占所有CP病例的70%。疼痛是最常见的临床特征。糖尿病和脂肪肝不常见。关于CP的诊断，所有专家都认为，患者在存在以下任何一种或多种情况下可被诊断为CP：内窥镜逆行胰胆管造影的导管改变、促胰液素试验阳性、胰腺钙化和提示CP的超声内镜异常。大多数专家建议将胰酶和镇痛药作为CP疼痛缓解的初始药物治疗。如果药物治疗失败，建议将内镜治疗作为首选治疗。只有在内镜治疗失败后才进行手术。大多数专家一致认为，研究应集中在遗传异常CP和endotherapy for pain relief.Conclusion的作用：调查带来了流行的类型和介绍CP，共同的管理实践，也在亚太地区CP的现有知识的缺点。这些发现可能有助于将注意力集中在该地区CP的研究重点上。(C)2004年Blackwell Publishing Asia Pty Ltd.
Background and Aims: A survey was conducted of chronic pancreatitis (CP) in different countries in the Asia-Pacific region. The main objective of the survey was to generate a database containing information regarding the prevalence, etiology, clinical presentation, diagnostic work-up, and management of CP in the Asia-Pacific region.Methods: Data were collected from seven countries using a structured questionnaire. Expert participants were asked to respond to the questionnaire based on the data of patients with CP studied in their centers.Results: The prevalence of CP was found to be very high in southern India (114-200/100 000 population), in contrast to the low reported rate of 4.2/100 000 population in Japan. Alcohol was the most common etiological factor in Australia (95%) and Japan (54%) while idiopathic pancreatitis was the most common type in India (tropical pancreatitis) and China, accounting for approximately 70% of all cases of CP. Pain was the most common clinical feature. Diabetes and steatorrhea were uncommon. With regard to the diagnosis of CP, all the experts believed that a patient could be diagnosed as having CP in the presence of any one or more of the following: ductal changes on endoscopic retrograde cholangiopancreatography, a positive secretin test, pancreatic calcification, and endosonographic abnormalities suggestive of CP. Most experts suggested pancreatic enzymes and analgesics as initial medical therapy for pain relief in CP. Endotherapy was suggested as the therapy of choice if medical therapy failed. Surgery was offered only after the failure of endotherapy. Most experts agreed that research should focus on genetic abnormalities in CP and the role of endotherapy for pain relief.Conclusion: The survey brought out the prevalent types and presentation of CP, common management practices, and also the shortcomings in the existing knowledge of CP in the Asia-Pacific region. These findings might help focus attention on the research priorities for CP in this region. (C) 2004 Blackwell Publishing Asia Pty Ltd.