Seasonal and Circadian Study of a Thymol/γ-Terpinene/p-Cymene Type Oil of Ocimum gratissimum L. and Its Antioxidant and Antifungal Effects
Seasonal and Circadian Study of a Thymol/γ-Terpinene/p-Cymene Type Oil of Ocimum gratissimum L. and Its Antioxidant and Antifungal Effects
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DOI：
10.21577/0103-5053.20180237
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发表时间：
2019-05-01
影响因子：
1.4
通讯作者：
Maia, José G. S.
中科院分区：
文献类型：
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作者：
Castro, Joaquim A. M. de;Monteiro, Odair S.;Maia, José G. S.
罗勒油具有高度的化学可变性，被广泛应用于医药、食品和化妆品等领域。当地企业已经考虑了对该工厂的经济开发。在巴西马萨诸塞州圣路易斯，用百里香酚和衍生油取样的标本，进行了季节性和昼夜节律研究，并进行了抗真菌和抗氧化分析。可以观察到，气候条件对产油量及其组成的变化有直接影响，主要是含氧单萜烃和单萜烯烃类，其中百里香酚、伽马松油烯和对伞花烃占主导地位。主成分分析(PCA)能够证明季节性(70%)和昼夜(86%)研究的油化学变异性是合理的。在0.3亩L毫升(-1)以上的浓度下，挥发油对黄褐斑病菌有明显的抑制作用，与百里香酚相比表现出更强的抑制活性。经2，2-二苯基-1-苦基肼(DPPH)自由基测定，其抗氧化性约为百里香酚的75%。
Ocimum gratissimum oil is used for various medicinal, food and cosmetic applications due to its high chemical variability. Local businesses have considered the economic exploitation of this plant. A specimen sampled at Sao Luis, MA, Brazil, with thymol and derivatives oil, was subjected to seasonal and circadian study, and to antifungal and antioxidant assays. It was possible to observe that the weather conditions showed a direct influence on the oil yield and variation of its constituents, mainly oxygenated monoterpenes and monoterpene hydrocarbons, with the predominance of thymol, gamma-terpinene, and p-cymene. Principal component analysis (PCA) was able to justify the oil chemical variability of the seasonal (70%) and circadian (86%) study. Oil displayed inhibition for the fungus Corynespora cassiicola at a concentration above 0.3 mu L mL(-1), and it showed a more significant activity by comparison to thymol. Using 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical assay, the oil antioxidant activity was about 75% of thymol.