Increased incidence of thyroid carcinoma in France:: A true epidemic or thyroid nodule management effects?: Report from the french thyroid cancer committee
Increased incidence of thyroid carcinoma in France:: A true epidemic or thyroid nodule management effects?: Report from the french thyroid cancer committee
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DOI：
10.1089/thy.2004.14.1056
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发表时间：
2004-12-01
期刊：
影响因子：
6.6
通讯作者：
Chérié-Challine, L
中科院分区：
文献类型：
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作者：
Leenhardt, L;Grosclaude, P;Chérié-Challine, L
在法国，甲状腺癌（TC）的发病率在过去二十年中急剧增加。为了尝试解释这一观察结果，法国卫生部要求公共卫生署协调一个多学科的甲状腺癌委员会（TCC）。TCC分析了法国TC发病率的时间趋势，评估了甲状腺疾病诊断实践的变化对观察到的TC增加的贡献，并制定了改进国家TC监测系统的指南。TC发病率的增加是真实的（女性和男性每年分别为8.1%和6.2%），主要是由于乳头状型，伴有微小癌的流行（43%的手术癌症，1998-2001年）与甲状腺切除术的广泛性有关。多中心研究显示，从1980年到2000年，超声检查（3%到84.8%）和细胞学检查（甲状腺结节患者的8%到36%）显著增加，手术患者中TC患病率的增加（12.5%到37%）与细针穿刺术的传播之间存在显著相关性。流行病学证据并不支持与切尔诺贝利事故有任何联系。TCC建议建立一个专门针对青少年甲状腺癌的国家登记册（
Thyroid cancer (TC) incidence, in France, has dramatically increased over the last two decades. In order to try and account for this observation, the French Department of Health requested the Public Health Agency to coordinate a multidisciplinary Thyroid Cancer Committee (TCC). The TCC analysed the temporal incidence trend in France, evaluated the contribution of changes in diagnostic practices of thyroid diseases to the observed increase of TC, and set up guidelines to improve the national surveillance system of TC.The increased incidence of TC is real (8.1% and 6.2% per year in women and in men, respectively), mainly due to papillary type with an epidemic of microcarcinomas (43% of operated cancers, period 1998-2001) associated to the extensiveness of thyroidectomies. Multicentric studies showed a significant increase, from 1980 to 2000, in ultrasonographic (3 to 84.8%) and cytological procedures (8 to 36% of patients with thyroid nodules) as well as a significant association between the increase in TC prevalence among operated patients (12.5 to 37%) and the spread of fine needle aspiration. Epidemiological evidence does not favour any link with the Chernobyl accident.The TCC recommended a national registry dedicated to thyroid cancer of the youths (