The tubule pathology of septic acute kidney injury: a neglected area of research comes of age.
The tubule pathology of septic acute kidney injury: a neglected area of research comes of age.
复制标题
DOI：
10.1038/ki.2011.401
复制
发表时间：
2012-02
影响因子：
19.6
通讯作者：
中科院分区：
文献类型：
--
作者：
Oxidant stress and compromised microcirculation underlie renal pathophysiology in septic acute kidney injury (AKI). Holthoff et al. report that resveratrol ameliorates these coupled abnormalities. They did not establish the primacy of either defect in septic AKI. However, tubule mitochondrial defects were recently reported to be involved in septic AKI pathogenesis, and resveratrol targets PGC-1α and respiratory enzymes. Together, these findings open new avenues for research into long-unresolved issues in the pathophysiology of septic AKI.
登录
查看更多内容
影响因子：
13.6
作者：
Weinberg, Joel M.
通讯作者：
Weinberg, Joel M.
影响因子：
15.9
作者：
Rowlands, David J.;Islam, Mohammad Naimul;Bhattacharya, Jahar
通讯作者：
Bhattacharya, Jahar
影响因子：
15.9
作者：
Tran, Mei;Tam, Denise;Parikh, Samir M.
通讯作者：
Parikh, Samir M.
影响因子：
4.3
作者：
Ruggieri AJ;Levy RJ;Deutschman CS
通讯作者：
Deutschman CS
影响因子：
13.6
作者：
Naito, Masayo;Bomsztyk, Karol;Zager, Richard A.
通讯作者：
Zager, Richard A.