PROCOGNATE: a cognate ligand domain mapping for enzymes

PROCOGNATE: a cognate ligand domain mapping for enzymes
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DOI:
10.1093/nar/gkm611
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发表时间:
2008-01-01
影响因子:
14.9
通讯作者:
Thornton, Janet M.
Thornton, Janet M.
中科院分区:
生物学2区
文献类型:
--
作者:
Bashton, Matthew;Nobeli, Irene;Thornton, Janet M.

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PROCOGNATE是一个由CATH、SCOP和Pfam描述的酶结构域的蛋白质同源配体数据库,可以作为交互式网站或平面文件获得。本文概述了数据库及其生成,并介绍了一个新的网站前端,以及最近通过包含Pfam域名在我们的数据集中增加的覆盖率。我们还描述了网站的导航及其功能。PROCOGNATE的当前版本(1.3)分别涵盖了CATH、SCOP和Pfam中的4123、4536、5876个结构和377、326、695个超家族/家族。PROCOGNATE可在http://www.ebi.ac.uk/thornton-srv/databases/procognate/上查阅。
PROCOGNATE is a database of protein cognate ligands for the domains in enzyme structures as described by CATH, SCOP and Pfam, and is available as an interactive website or a flat file. This article gives an overview of the database and its generation and presents a new website front end, as well as recent increased coverage in our dataset via inclusion of Pfam domains. We also describe navigation of the website and its features. The current version (1.3) of PROCOGNATE covers 4123, 4536, 5876 structures and 377, 326, 695 superfamilies/families in CATH, SCOP and Pfam, respectively. PROCOGNATE can be accessed at: http://www.ebi.ac.uk/thornton-srv/databases/procognate/.