The repairability of oxidative free radical mediated damage to DNA: a review.
The repairability of oxidative free radical mediated damage to DNA: a review.
复制标题
氧化自由基介导的 DNA 损伤的可修复性:综述。
DOI:
--
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发表时间:
1988
影响因子:
2.6
通讯作者:
Jean Cadet
中科院分区:
文献类型:
--
作者:
G. Teebor;R. Boorstein;Jean Cadet
Many DNA repair enzyme activities are present in both prokaryotic and eukaryotic organisms. Among these are DNA exo- and endonucleases and DNA glycosylases which remove oxidatively damaged portions of the DNA molecule, thereby initiating excision-repair. The existence of these enzymes may be taken as evidence that cellular DNA is continuously subject to endogenous oxidative stress. Many of the lesions introduced by ionizing and ultraviolet radiation are identical to those introduced into DNA by reactive oxygen species generated by activated white cells, and are substrates for the repair enzymes. The chemical nature of the lesions, their biologic effects, and the mechanism of their repairability are described.
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影响因子:
11.2
作者:
Boorstein,RJ;Levy,DD;Teebor,GW
通讯作者:
Teebor,GW
影响因子:
14.9
作者:
CLARK, JM;BEARDSLEY, GP
通讯作者:
BEARDSLEY, GP
DOI:
10.1016/0027-5107(87)90267-3
发表时间:
1987
期刊:
Mutation research
影响因子:
--
作者:
Shirnamé-Moré,L;Rossman,TG;Troll,W;Teebor,GW;Frenkel,K
通讯作者:
Frenkel,K
影响因子:
3.4
作者:
S. Chiu;L. Friedman;N. M. Sokany;L. Xue;N. Oleinick
通讯作者:
S. Chiu;L. Friedman;N. M. Sokany;L. Xue;N. Oleinick
DOI:
10.3109/10715768709065296
发表时间:
1987
期刊:
Free radical research communications
影响因子:
--
作者:
Teebor,G;Cummings,A;Frenkel,K;Shaw,A;Voituriez,L;Cadet,J
通讯作者:
Cadet,J