Direct observation of the hydrocarbon chain tilt angle in phospholipid bilayers.
Direct observation of the hydrocarbon chain tilt angle in phospholipid bilayers.
复制标题
直接观察磷脂双层中的烃链倾斜角。
DOI：
10.1016/s0006-3495(79)85289-3
复制
发表时间：
1979
影响因子：
3.4
通讯作者：
D. Moncton
中科院分区：
文献类型：
--
作者：
J. Stamatoff;W. Graddick;L. Powers;D. Moncton
通过X射线衍射，我们观察到的倾斜的烃链内的二棕榈酰磷脂酰胆碱多层膜。倾斜在（4.2 A）-1区域中产生强度分布，其提供倾斜角的定量测量。最近开发的方法制备的多层膜和安装，形成一个“独立的”样品的详细衍射研究，使得在这个区域的强度的准确测量成为可能。我们发现的强度分布是从以前报道的不同，并着手开发一个新的模型倾斜链。该模型允许计算作为倾斜角的函数的强度分布，然后将其拟合到数据。
By means of X-ray diffraction we have observed the tilting of hydrocarbon chains within a dipalmitoyl phosphatidylcholine multilayer. The tilting produces a distribution of intensity in the (4.2 A)-1 region that provides a quantitative measure of the angle of tilt. Detailed diffraction investigation of multilayers prepared by a recently developed method and mounted to form a "freestanding" sample has made possible the accurate measurement of intensity in this region. We find the intensity distribution to be different from that previously reported and proceed to develop a new model for tilted chains. The model permits calculation of the intensity distribution as a function of tilt angle which is then fit to the data.