Sequence and organization of the mitochondrial genome of the Chagas disease vector, Triatoma dimidiata
Sequence and organization of the mitochondrial genome of the Chagas disease vector, Triatoma dimidiata
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DOI：
10.1046/j.1365-2583.2001.00258.x
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发表时间：
2001-06-01
影响因子：
2.6
通讯作者：
Beard, CB
中科院分区：
文献类型：
--
作者：
Dotson, EM;Beard, CB
Triatoma dimidiata线粒体基因组全长17019 bp，由13个蛋白质编码序列、22个trna、大小核糖体单元和一个控制区组成。该基因的顺序和取向与雅库巴果蝇相同。核苷酸组成偏向腺嘌呤和胸腺嘧啶（69.5% A + T）。2.1 kb的假定控制区，在大多数昆虫中被称为A + T富区，具有66%的A + T偏倚，但包含400 bp的序列，其中77.5%为A + T，以及另外两个不同的区域：(1)A + T偏倚较低的区域（60.1%）和(2)8个串联重复单元的区域。鉴定出的线粒体序列1.4 kb的核拷贝包含Gs序列和细胞色素c氧化酶1基因的开始，但缺乏1.8 kb的区域，跨越8个串联重复序列和NADH脱氢酶II基因的5'端。
The 17 019 bp mitochondrial genome of Triatoma dimidiata is composed of thirteen protein coding sequences, twenty-two tRNAs, small and large ribosomal units, and a control region. The gene order and orientation are identical to that of Drosophila yakuba. The nucleotide composition is biased toward adenine and thymine (69.5% A + T). The 2.1 kb putative control region, known as the A + T rich region in most insects, has an A + T bias of 66%, but contains a 400 bp sequence that is 77.5% A + T and two other distinct regions: (1) one with a lower A + T bias (60.1%) and (2) a region of eight tandem repeat units.The identified 1.4 kb nuclear copy of mitochondrial sequences encompasses the string of Gs and the beginning of the cytochrome c oxidase 1 gene but lacks the 1.8 kb region spanning the eight tandem repeats and the 5' end of the NADH dehydrogenase subunit II gene.