Deteriorating Epilepsies: Severely Deteriorated Cases
Deteriorating Epilepsies: Severely Deteriorated Cases
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癫痫恶化：严重恶化的病例
DOI：
10.1111/j.1440-1819.1990.tb01407.x
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发表时间：
1990
期刊：
影响因子：
--
通讯作者：
T. Onuma
中科院分区：
文献类型：
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作者：
T. Onuma
摘要：我院12年来共收治严重恶化癫痫患者28例。在这28例病例中，22例恶化的病因被认为是由于反复难治性癫痫发作或抗癫痫药物（aed）或两者兼而有之。尽管在许多病例中难以鉴别诊断其病因，即癫痫发作与aed，但在6例病例中，我们认为aed在其恶化中起主要作用。本文详细介绍了这类案例。特别强调的是，他们经常表现出急性共济失调和精神错乱的发作，通常与发热性疾病有关。他们经历了一个急性或亚急性加重和部分缓解的过程。讨论了这些恶化的性质和可能的避免办法。
Abstract: A total of 28 cases of severely deteriorated epileptic patients were seen at out‐ and inpatient services in the past 12 years. In 22 out of these 28 cases, the etiology for the deterioration was considered to be due to either repetitive intractable seizures or antiepileptic drugs (AEDs) or both. Although differential diagnoses were difficult in many cases as to the responsible causes, namely seizure vs. AEDs, it was considered in 6 cases that AEDs took a major role in their deterioration. Details of such cases are presented. Special emphasis was made to the fact in which they frequently showed episodes of acute ataxia and confusion often associated with febrile illness. They took a course of acute or subacute exacerbation and partial remission. Discussion was held on the nature and possible avoidance of these deteriorations.