Spontaneous resolution of systemic sarcoidosis in a patient with chronic hepatitis C without interferon therapy.
Spontaneous resolution of systemic sarcoidosis in a patient with chronic hepatitis C without interferon therapy.
复制标题
慢性丙型肝炎患者的系统性结节病无需干扰素治疗即可自然消退。
DOI：
10.3748/wjg.v12.i1.150
复制
发表时间：
2006
影响因子：
4.3
通讯作者：
J. Joo
中科院分区：
文献类型：
--
作者：
Tae‐Hun Kim;J. Joo
一名39岁男性患者主诉双手关节痛，经评估发现患有慢性丙型肝炎和累及肺、皮肤、肝脏和脾脏的全身性结节病。组织学检查发现大量非干酪化性肉芽肿，证实为肝和皮肤结节病。影像学检查诊断为肺和脾受累。15个月后，肺、肝和脾的结节样病变通过放射学研究消退，肝活检显示无肉芽肿，但有中度至重度炎症活动。系统性结节病是一种罕见的慢性丙型肝炎合并症，可自行消退。
A 39-year-old male patient complaining of bilateral hand joint arthralgia was evaluated and found to have chronic hepatitis C and systemic sarcoidosis involving lung, skin, liver, and spleen. Hepatic and cutaneous sarcoidoses were confirmed by the presence of numerous noncaseating granulomas on histological examination. Pulmonary and splenic involvements were diagnosed by imaging studies. Fifteen months later, the sarcoidotic lesions in lung, liver, and spleen were resolved by radiological studies and a liver biopsy showed no granuloma but moderate to severe inflammatory activity. systemic sarcoidosis is a rare comorbidity of chronic hepatitis C which may spontaneously resolve.