Identification of Novel Phosphorus-Based Flame Retardants in Curtains Purchased in Japan Using Orbitrap Mass Spectrometry
Identification of Novel Phosphorus-Based Flame Retardants in Curtains Purchased in Japan Using Orbitrap Mass Spectrometry
复制标题
DOI：
10.1021/acs.estlett.8b00263
复制
发表时间：
2018-06
影响因子：
10.9
通讯作者：
Y. Miyake;M. Tokumura;Qi Wang;T. Amagai;Yasuhiro Takegawa;Yoko Yamagishi;Sayaka Ogo;Kazunari Kume;Takeshi Kobayashi;S. Takasu;K. Ogawa;K. Kannan
中科院分区：
文献类型：
--
作者：
Y. Miyake;M. Tokumura;Qi Wang;T. Amagai;Yasuhiro Takegawa;Yoko Yamagishi;Sayaka Ogo;Kazunari Kume;Takeshi Kobayashi;S. Takasu;K. Ogawa;K. Kannan
开发了一种分析方法，通过使用与混合四极轨道阱质谱仪（LC-Orbitrap-MS; Q Exactive Plus）连接的液相色谱仪，筛选和鉴定2014年在日本购买的窗帘中的新型阻燃剂。为了能够完全提取窗帘中的阻燃剂，我们使用了早期开发的提取方法，其中使用1，1，1，3，3，3-六氟-2-丙醇/氯仿（1：4，v/v）的溶剂混合物来完全溶解窗帘基质。最初的气相色谱-质谱扫描分析证实了窗帘中存在几种不明阻燃剂。然后，我们通过使用LC-Orbitrap-MS确定检测到的化合物的精确质量，并使用该信息构建检测到的化合物的化学式。然后使用MAGMa在线光谱数据注释来生成候选化合物列表。为了确定和确证候选化合物的化学结构，我们对文献进行了综述。
An analytical method was developed for screening and identifying novel flame retardants in curtains purchased in Japan in 2014 by use of a liquid chromatograph interfaced with a hybrid quadrupole Orbitrap mass spectrometer (LC–Orbitrap-MS; Q Exactive Plus). To enable complete extraction of flame retardants in curtains, we used an extraction method developed earlier, in which a solvent mixture of 1,1,1,3,3,3-hexafluoro-2-propanol/chloroform (1:4, v/v) was used to completely dissolve the curtain matrix. An initial gas chromatography–MS scan analysis confirmed the presence of several unidentified flame retardants in curtains. We then determined the precise masses of the detected compounds by use of a LC–Orbitrap-MS and used that information to construct chemical formula of the detected compounds. The MAGMa online spectral data annotation was then used to generate a list of candidate compounds. For the determination and confirmation of the chemical structures of the candidate compounds, we reviewed the litera...