High prevalence of human bocavirus detected in young children with severe acute lower respiratory tract disease by use of a standard PCR protocol and a novel real-time PCR protocol
High prevalence of human bocavirus detected in young children with severe acute lower respiratory tract disease by use of a standard PCR protocol and a novel real-time PCR protocol
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DOI：
10.1128/jcm.01884-06
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发表时间：
2007-03-01
影响因子：
9.4
通讯作者：
Haeusler, Martin
中科院分区：
文献类型：
--
作者：
Kleines, Michael;Scheithauer, Simone;Haeusler, Martin
人类博卡病毒（HBoV）是最近从呼吸道样本中分离出来的。在患有严重下呼吸道疾病的儿童的研究集体中，HBoV检测阳性的患者（12.8%）具有更高的潜在心肺疾病率。呼吸道标本中的病毒载量范围为10（2）至10（10）基因组当量/ml。
The human bocavirus (HBoV) was recently isolated from respiratory tract samples. Within a study collective of children with severe lower respiratory tract disease, the patients testing positive for HBoV (12.8%) had a higher rate of underlying cardiopulmonary disease. Viral loads in respiratory tract specimens varied from 10(2) to 10(10) genome equivalents/ml.