A meta-analysis of randomized controlled trials on acupuncture for amblyopia.
A meta-analysis of randomized controlled trials on acupuncture for amblyopia.
复制标题
针灸治疗弱视随机对照试验的荟萃分析
DOI：
10.1155/2013/648054
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
Wang J
中科院分区：
文献类型：
--
作者：
Yan X;Zhu T;Ma C;Liu A;Dong L;Wang J
目的：评估针灸治疗弱视的有效性和安全性证据，并分析其临床应用现状。方法：我们系统检索了万方、重庆维普中文科技期刊数据库（VIP）、中国知网（CNKI）和PubMed。确定了已发表的评估针灸与常规治疗相比治疗弱视效果的随机对照试验（RCT）和对照临床试验（CCT）。根据Jadad量表评估纳入试验的方法学质量。使用RevMan 5.1进行数据合成。结果：14项试验共涉及2662名参与者，满足荟萃分析的最低标准。证据表明，针灸组内的治疗总有效率高于常规治疗组；组间差异具有统计学意义（合并随机效应模型（RR）=1.17，95%置信区间（1.11，1.24），Z = 5.56，P < 0.00001）。结论：针灸治疗弱视的总有效率明显优于常规治疗，表明针灸是一种有前途的弱视治疗方法。然而，由于CCT和RCT数量有限，特别是大样本量和多中心随机对照研究数量不足，在有更高质量的进一步研究之前，我们无法得出完全肯定的结论。
Objective. To assess the evidence of efficacy and safety of acupuncture for amblyopia and analyze the current situation of its clinical setting. Methods. We systemically searched Wanfang, Chongqing Weipu Database for Chinese Technical Periodicals (VIP), China National Knowledge Infrastructure (CNKI), and PubMed. Published randomized controlled trials (RCT) and controlled clinical trials (CCT) that evaluated the effect of acupuncture for amblyopia compared with conventional treatment were identified. The methodological quality of the included trials was assessed based on the Jadad scale. Data synthesis was facilitated using RevMan 5.1. Results. Fourteen trials involving 2662 participants satisfied the minimum criteria for meta-analysis. The evidence showed that the total effective rate of treatment within the group receiving acupuncture was higher than that in conventional group; there were statistically significant differences between groups (polled random effects model (RR) = 1.17, 95% confidence interval (1.11, 1.24), Z = 5.56, P < 0.00001). Conclusion. The total effective rate of acupuncture for amblyopia was significantly superior to conventional treatment, indicating that acupuncture was a promising treatment for amblyopia. However, due to the limited number of CCTs and RCTs, especially those of large sample size and multicenter randomized controlled studies that were quantitatively insufficient, we could not reach a completely affirmative conclusion until further studies of high quality are available.
DOI：
10.1016/0197-2456(95)00134-4
发表时间：
1996-02-01
期刊：
CONTROLLED CLINICAL TRIALS
影响因子：
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作者：
Jadad, AR;Moore, RA;McQuay, HJ
通讯作者：
McQuay, HJ
影响因子：
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作者：
Jadad, AR;Moher, M;Stevens, R
通讯作者：
Stevens, R