Role of imaging in drug-related osteonecrosis of the jaw: an up-to-date review.
Role of imaging in drug-related osteonecrosis of the jaw: an up-to-date review.
复制标题
影像学在药物相关性颌骨坏死中的作用：最新综述。
DOI：
10.1016/j.jdsr.2018.11.004
复制
发表时间：
2019
期刊：
影响因子：
6.6
通讯作者：
Kurabayashi T.
中科院分区：
文献类型：
--
作者：
Tsuchimochi M;Kurabayashi T.
MRONJ/ARONJ是一种严重的药物不良反应，虽然发病率很低，但关于MRONJ/ARONJ的发病机制仍存在争议。可导致MRONJ/ARONJ的药物通常用于治疗骨质疏松症和预防恶性肿瘤骨转移引起的骨折。ONJ的长期疾病状态恶化了受影响患者的生活质量。早期发现和预防这种疾病是减轻疼痛和不适的关键。迄今为止，已经引入了几种成像模式来描述病变。影像学检查、X线摄影、CT、MRI和核医学为管理这种具有挑战性的疾病提供了重要信息。
MRONJ/ARONJ is a serious adverse effect of medication, although the incidence of the disease is rare, and there are still controversial issues regarding the pathogenesis of MRONJ/ARONJ. Medications that can lead to MRONJ/ARONJ are commonly used to treat osteoporosis and to prevent bone fractures caused by bone metastasis of malignancies. The long-standing disease state of ONJ deteriorates the quality of life of affected patients. Early detection and prevention of the disease are key to alleviating pain and discomfort. To date, several imaging modalities have been introduced to depict the lesions. Imaging modalities, radiography, CT, MRI and nuclear medicine provide important information for managing this challenging disease.