Diffusion tensor and volumetric magnetic resonance imaging findings in the brains of professional musicians
Diffusion tensor and volumetric magnetic resonance imaging findings in the brains of professional musicians
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DOI：
10.1016/j.jchemneu.2017.11.003
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发表时间：
2018-03-01
影响因子：
2.8
通讯作者：
Ozic, Muhammet Usame
中科院分区：
文献类型：
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作者：
Acer, Niyazi;Bastepe-Gray, Serap;Ozic, Muhammet Usame
职业音乐家是研究训练引起的大脑可塑性的理想模型。本研究旨在利用结构磁共振和扩散张量成像（DTI）研究音乐家的脑容量和扩散特征。结合体积法和扩散法对音乐家大脑的研究尚未见文献报道。我们的研究小组由7名演奏乐器的男性音乐家和7名年龄和性别匹配的非音乐家组成。我们评估了灰质（GM）、白质（WM）和脑脊液（CSF）的体积，计算了总颅内体积（TIV），并测量了预先选择的脑脊髓束的分数各向异性（FA）：胼胝体（CC）、皮质脊髓束（CST）、上纵束（SLF）、大产子（ForMaj）、小产子（ForMin）和弓状束（AF）。与非音乐家相比，音乐家的平均WM/TIV音量更高。音乐家的CC、SLF、ForMaj、ForMin和右AF的平均FA较低，但右CST的平均FA较高。音乐家的CST、SLF、左心房和ForMaj的纤维总数平均值较大。各组间比较差异无统计学意义（p < 0.05）。然而，与非音乐家相比，音乐家的左右小脑、边缘上回和角回、左侧顶叶上小叶和顶叶下小叶以及左侧颞中回的GM体积增加。我们的发现表明音乐家的大脑结构不同，并且在更大的人群中证实了这一结果。
Professional musicians represent an ideal model to study the training-induced brain plasticity. The current study aimed to investigate the brain volume and diffusion characteristics of musicians using structural magnetic resonance and diffusion tensor imaging (DTI). The combined use of volumetric and diffusion methods in studying musician brain has not been done in literature. Our study group consisted of seven male musicians playing an instrument and seven age- and gender-matched non-musicians. We evaluated the volumes of gray matter (GM), white matter (WM), and cerebrospinal fluid (CSF) and calculated total intracranial volume (TIV) and measured the fractional anisotropy (FA) of pre-selected WM bundles: corpus callosum (CC), corticospinal tract (CST), superior longitudinal fasciculus (SLF), forceps major (ForMaj), forceps minor (ForMin), and arcuate fasciculus (AF). The mean WM/TIV volume in musicians was higher compared to non-musicians. The mean FA was lower in CC, SLF, ForMaj, ForMin, and right AF but higher in right CST in the musicians. The mean value of the total number of fibers was larger in the CST, SLF, left AF, and ForMaj in the musicians. The observed differences were not statistically significant between the groups (p>0.05). However, increased GM volume was found in the musicians compared to the non-musicians in the right and left cerebellum and supramarginal and angular gyrus, left superior and inferior parietal lobule and as well as left middle temporal gyrus. Our findings suggest differing brain structure in musicians and the confirmation of the results on a larger population.