When to Stop Detrimental Effect of Device Passes in Acute Ischemic Stroke Secondary to Large Vessel Occlusion
When to Stop Detrimental Effect of Device Passes in Acute Ischemic Stroke Secondary to Large Vessel Occlusion
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DOI：
10.1161/strokeaha.119.025088
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发表时间：
2019-07-01
期刊：
影响因子：
8.3
通讯作者：
Ribo, Marc
中科院分区：
文献类型：
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作者：
Garcia-Tornel, Alvaro;Requena, Manuel;Ribo, Marc
背景和目的-大血管闭塞导致的急性缺血性卒中成功再通的患者中，有相当一部分没有获得良好的功能结局。我们的目的是分析血栓切除器械通过次数和再通程度（通过改良脑梗死溶栓）对临床和功能结局的影响。方法：在一个三级卒中中心，542名连续患者接受了前循环大血管闭塞的机械血栓切除术。记录基线特征、通过次数、再通程度、24小时的临床结局（通过美国国立卫生研究院量表评分测量）和功能结局（通过90天时的改良兰金量表测量）。进行多变量分析，以确定通过次数和再通程度与临床恢复（最终国立卫生研究院量表评分）的相关性
Background and Purpose- Substantial proportion of patients who achieve successful recanalization of acute ischemic stroke due to large vessel occlusion do not achieve good functional outcome. We aim to analyze the effect of number of thrombectomy device passes and degree of the recanalization (by modified Thrombolysis in Cerebral Infarction) on the clinical and functional outcome. Methods- Five hundred forty-two consecutive patients underwent mechanical thrombectomy for large vessel occlusion in the anterior circulation at a single tertiary stroke center. Baseline characteristics, number of passes, recanalization degree, clinical outcome at 24 hours (measured by National Institutes of Health Scale score), and functional outcome (measured by modified Rankin Scale at 90 days) were registered. Multivariate analysis was performed to determine the association of number of passes and degree of recanalization with dramatical clinical recovery (final National Institutes of Health Scale score