[Optimization of ultrasonic extraction conditions of safflower yellow from Carthamus tinctorius by response surface methodology].

[Optimization of ultrasonic extraction conditions of safflower yellow from Carthamus tinctorius by response surface methodology].
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DOI:
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发表时间:
2013-12
期刊:
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
影响因子:
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通讯作者:
Yan-wen Sun;Yu He;Ruping Zhang;Jia-wei Huang;Man-cang Gu
Yan-wen Sun;Yu He;Ruping Zhang;Jia-wei Huang;Man-cang Gu
中科院分区:
其他
文献类型:
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作者:
Yan-wen Sun;Yu He;Ruping Zhang;Jia-wei Huang;Man-cang Gu

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OBJECTIVE To investigate the optimization of extraction conditions of safflower yellow from Cartbamus tirwtorius by response surface methodology. METHODS Experimental factors and levels were selected by one-factor test, and then according to the central composite experimental design principle, response surface'-methodology with three factors and three levels was used to establish a mathematical model to obtain the optimal extraction conditions with hydroxysafflower yellow A being the target and its extraction yield as response value. RESULTS The optimal extraction conditions of safflower yellow were as follows: extraction temperature was 55 t, ratio of water to raw material was 16:1 and extraction time was 39 mm for three times. CONCLUSION Under these conditions, the extraction yield of safflower yellow is 1.798%, and the relative error between the predicted value with actual value is 2.758%. The optimized method can provide reference for the efficient extraction of safflower yellow from Carthomos tinctorius