THE TOUSLED GENE IN A-THALIANA ENCODES A PROTEIN-KINASE HOMOLOG THAT IS REQUIRED FOR LEAF AND FLOWER DEVELOPMENT
THE TOUSLED GENE IN A-THALIANA ENCODES A PROTEIN-KINASE HOMOLOG THAT IS REQUIRED FOR LEAF AND FLOWER DEVELOPMENT
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DOI：
10.1016/0092-8674(93)90537-z
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发表时间：
1993-12-03
期刊：
影响因子：
64.5
通讯作者：
ZAMBRYSKI, PC
中科院分区：
文献类型：
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作者：
ROE, JL;RIVIN, CJ;ZAMBRYSKI, PC
在A. thaliana导致复杂的表型，其中最引人注目的方面是在突变植物中产生的异常花。TSL花表现出花器官的随机损失，并且器官发育受损。TSL基因似乎是必需的花分生组织正确启动花器官原基和器官原基的适当发展。TSL功能的丧失也影响开花时间和叶形态。利用T-DNA插入突变，我们已经克隆了TSL基因，发现它编码一个蛋白激酶同源物与一个新的N-末端结构域。该蛋白激酶基因鉴定了拟南芥发育过程中使用的一种新的信号/调节途径。
Mutation at the TOUSLED locus of A. thaliana results in a complex phenotype, the most dramatic aspect of which being the abnormal flowers produced in mutant plants. tsl flowers show a random loss of floral organs, and organ development is impaired. The TSL gene appears to be required in the floral meristem for correct initiation of floral organ primordia and for proper development of organ primordia. Loss of TSL function also affects flowering time and leaf morphology. Using a mutation derived by T-DNA insertion mutagenesis, we have cloned the TSL gene and found that it encodes a protein kinase homolog with a novel N-terminal domain. This protein kinase gene identifies a novel signaling/regulatory pathway used during development in Arabidopsis.