25th Anniversary Article: Double Emulsion Templated Solid Microcapsules: Mechanics And Controlled Release
25th Anniversary Article: Double Emulsion Templated Solid Microcapsules: Mechanics And Controlled Release
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DOI：
10.1002/adma.201305119
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发表时间：
2014-04-01
影响因子：
29.4
通讯作者：
Weitz, David A.
中科院分区：
文献类型：
--
作者：
Datta, Sujit S.;Abbaspourrad, Alireza;Weitz, David A.
描述了如何使用液滴微流体来制造具有精确控制释放行为的固体壳微胶囊。玻璃毛细管装置能够生产单分散的双重乳液液滴，然后可以将其用作微胶囊形成的模板。微流体技术提供的精密控制可用于以优异的精度调整微胶囊的组成和几何特性。使用这种方法来制造微胶囊，只有释放其内容时，暴露于特定的刺激-如温度的变化，暴露于光，化学环境的变化，或外部应力-只有在规定的时间延迟后，并在规定的速率进行审查。
How droplet microfluidics can be used to fabricate solid-shelled microcapsules having precisely controlled release behavior is described. Glass capillary devices enable the production of monodisperse double emulsion drops, which can then be used as templates for microcapsule formation. The exquisite control afforded by microfluidics can be used to tune the compositions and geometrical characteristics of the microcapsules with exceptional precision. The use of this approach to fabricate microcapsules that only release their contents when exposed to a specific stimulus - such as a change in temperature, exposure to light, a change in the chemical environment, or an external stress - only after a prescribed time delay, and at a prescribed rate is reviewed.